Dielectric components of charge movements in skeletal muscle

The Journal of Physiology
C L Huang

Abstract

1. Voltage clamp experiments measured transients from 10 mV steps applied about different membrane potentials, VT. Their analysis employed the Fourier transform relationship between dielectric spectra of permittivity as a function of frequency, and the step transient admittance, as well as established methods. 2. The membrane capacitance measured between -85 mV and about -50 mV rose monotonically and was associated with simple decaying transients in both 'on' and 'off' steps. At more depolarized potentials the capacitance increased sharply and was associated with a charging current of complex form, before falling again beyond the transition potential. 3. Step-transient responses for dielectric analysis were sampled in the above voltage range. Dielectric spectra of the non-linear transients were obtained by subtracting Fourier transforms of transients at VC = -85 mV from test transforms at VT. 4. The imaginary transform coefficients represent a spectrum of dielectric loss against frequency. These showed two non-linear components. The q beta component formed a broad peak, when charge movements were simple monotonic decays. A sharp low-frequency q gamma peak became superimposed at particular voltages when charge-movement kinetics ...Continue Reading

Citations

Jan 1, 1985·Progress in Biophysics and Molecular Biology·J CailléO Rougier
Jul 10, 2004·The Journal of Physiology·James A Fraser, Christopher L-H Huang
Feb 1, 1985·Pflügers Archiv : European journal of physiology·S Takashima
Apr 22, 1982·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·S Duane, C L Huang
Oct 14, 2011·Journal of Muscle Research and Cell Motility·Christopher L-H HuangJames A Fraser

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