Dielectrophoresis Manipulation: Versatile Lateral and Vertical Mechanisms

Biosensors
Muhamad Ramdzan BuyongBurhanuddin Yeop Majlis

Abstract

Discussing the topic of the capability of dielectrophoresis (DEP) devices in terms of the selective detection and rapid manipulation of particles based on the DEP force (FDEP) via contactless methods is challenging in medical research, drug discovery and delivery. Nonetheless, the process of the selective detection and rapid manipulation of particles via contactless DEP based on dielectric particles and the surrounding medium can reduce the effects of major issues, including physical contact with the particles and medium contamination to overcome operational difficulties. In this review, DEP microelectromechanical system (MEMS) microelectrodes with a tapered profile for the selective detection and rapid manipulation of particles were studied and compared with those of conventional designs with a straight-cut profile. The main objective of this manuscript is to review the versatile mechanism of tapered DEP MEMS microelectrodes for the purpose of selective detection and rapid manipulation. Thus, this review provides a versatile filtration mechanism with the potential for a glomerular-based membrane in an artificial kidneys' development solution for implementing engineered particles and cells by lateral attraction as well as verti...Continue Reading

References

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Citations

Sep 15, 2020·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Akihisa Miyagawa, Tetsuo Okada
Apr 4, 2021·Micromachines·Honeyeh Matbaechi Ettehad, Christian Wenger
Apr 20, 2021·Luminescence : the Journal of Biological and Chemical Luminescence·Lu Ning ZhuJian Wang
Jul 25, 2020·ACS Applied Materials & Interfaces·Tuo ZhouLawrence Kulinsky
Aug 29, 2021·Biotechnology Advances·Kexin WangPau Loke Show
Dec 4, 2021·Electrophoresis·Revathy DeivasigamaniMuhamad Ramdzan Buyong

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Methods Mentioned

BETA
membrane
fluorescence-activated cell sorting
membrane filtration

Software Mentioned

FEM COMSOL
Matlab
ApoStream TM3

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