Abstract
In recent years, dielectrophoretic force has been used to manipulate colloids, inert particles, and biological microparticles, such as red blood cells, white blood cells, platelets, cancer cells, bacteria, yeast, microorganisms, proteins, DNA, etc. This specific electrokinetic technique has been used for trapping, sorting, focusing, filtration, patterning, assembly, and separating biological entities/particles suspended in a buffer medium. Dielectrophoretic forces acting on particles depend on various parameters, for example, charge of the particle, geometry of the device, dielectric constant of the medium and particle, and physiology of the particle. Therefore, to design an effective micro-/nanofluidic separation platform, it is necessary to understand the role of the aforementioned parameters on particle motion. In this paper, we review studies particularly related to dielectrophoretic separation in microfluidic devices. Both experimental and theoretical works by several researchers are highlighted in this article covering AC and DC DEP. In addition, AC/DC DEP, which uses a combination of low frequency AC and DC voltage to manipulate bioparticles, has been discussed briefly. Contactless DEP, a variation of DC DEP in which ele...Continue Reading
References
Mar 1, 1978·The American Journal of Cardiology·R V LuepkerJ R Warbasse
May 21, 1979·Journal of Theoretical Biology·A IrimajiriA Inouye
Mar 1, 1978·The Journal of Clinical Investigation·M H Humphreys, J C Ayus
Jan 1, 1989·Biopolymers·P De SantisM Savino
Dec 19, 1984·Biochimica Et Biophysica Acta·K Asami, A Irimajiri
Aug 20, 1993·Biochimica Et Biophysica Acta·M WashizuK V Kaler
May 14, 1993·Science·R Langer, J P Vacanti
Jan 1, 1996·Neuroscience·V Maienschein, H Zimmermann
Jan 31, 1997·Biochimica Et Biophysica Acta·P GascoyneM Ruchirawat
Apr 15, 1997·Analytical Chemistry·P C Li, D J Harrison
Nov 14, 1997·Trends in Biotechnology·R Pethig, G H Markx
Jul 2, 1999·Biophysical Journal·H MorganN G Green
Apr 25, 2000·Biophysical Journal·J YangP R Gascoyne
Feb 13, 2001·Biophysical Journal·J VoldmanM A Schmidt
Mar 14, 2002·Electrophoresis·Elisabeth Verpoorte
Sep 5, 2002·Electrophoresis·Charles L AsburyGer van den Engh
Sep 5, 2002·Electrophoresis·Peter R C Gascoyne, Jody Vykoukal
Sep 27, 2002·Biophysical Journal·Chia-Fu ChouRobert H Austin
Mar 12, 2003·Advanced Drug Delivery Reviews·Bernhard H WeiglCatherine R Cabrera
Nov 13, 2003·Electrophoresis·Samuel K Sia, George M Whitesides
Nov 13, 2003·Electrophoresis·Adrienne R MinerickHsueh-Chia Chang
Dec 17, 2003·Analytical Chemistry·Eric B Cummings, Anup K Singh
Mar 11, 2004·IEEE Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society·Thomas B Jones
Mar 11, 2004·IEEE Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society·Chia-Fu Chou, Frederic Zenhausern
Mar 17, 2004·Analytical Chemistry·Blanca H Lapizco-EncinasYolanda Fintschenko
Apr 22, 2004·Lab on a Chip·Peter GascoyneFrederick F Becker
Jun 10, 2004·Electrophoresis·Blanca H Lapizco-EncinasYolanda Fintschenko
Jul 23, 2004·Lab on a Chip·Peter R C GascoyneCraig Andrews
Jul 29, 2004·Journal of Microbiological Methods·Esther G CenKaran V I S Kaler
Dec 23, 2004·Biophysical Journal·Adam Rosenthal, Joel Voldman
Mar 31, 2005·Journal of Colloid and Interface Science·Hao ZhouRobert D Tilton
Jul 26, 2005·Journal of Chromatography. a·Carlos F Gonzalez, Vincent T Remcho
Dec 31, 2005·Electrophoresis·Kwan Hyoung KangDongqing Li
Feb 2, 2006·Lab on a Chip·Irena Barbulovic-NadDongqing Li
Mar 29, 2006·Electrophoresis·Ronghui ZhouHsueh-Chia Chang
Jul 13, 2006·Annual Review of Biomedical Engineering·Joel Voldman
Aug 4, 2006·Journal of Chromatography. a·Fredrik AldaeusJohan Roeraade
Feb 3, 2007·Lab on a Chip·Youlan LiKaran V I S Kaler
Mar 3, 2007·Lab on a Chip·Nicolas DemierrePhilippe Renaud
Sep 4, 2007·Analytical Chemistry·Benjamin G HawkinsBrian J Kirby
Sep 28, 2007·Biomedical Microdevices·Yuejun KangJosiane E Eid
Dec 12, 2007·Electrophoresis·Blanca H Lapizco-Encinas, Marco Rito-Palomares
Jun 24, 2008·Journal of Chromatography. a·Blanca H Lapizco-EncinasMarco Rito-Palomares
Jan 9, 2009·Electrophoresis·Soumya K SrivastavaAdrienne R Minerick
Mar 24, 2009·Electrophoresis·Peter R C GascoyneFrederick F Becker
May 6, 2009·Biomedical Microdevices·Hadi ShafieeRafael V Davalos
Jan 1, 2004·Proceedings of the IEEE·Peter R C Gascoyne, Jody V Vykoukal
Sep 2, 2009·Analytica Chimica Acta·Xiaojun FengBi-Feng Liu
Oct 27, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Ye AiShizhi Qian
Oct 30, 2009·Lab on a Chip·I-Fang ChengHsien-Chang Chang
Citations
Dec 8, 2014·The Journal of Chemical Physics·Jennifer Galanis, Yoav Tsori
Dec 8, 2015·Electrophoresis·Yongxin SongDongqing Li
Dec 9, 2015·Electrophoresis·Markus KnoerzerKhashayar Khoshmanesh
Jul 28, 2015·International Journal of Molecular Sciences·Shih-Jie Lo, Da-Jeng Yao
Jan 26, 2016·Biotechnology Journal·Yi-Je Juang, Jo-Shu Chang
Nov 17, 2015·Analytical Chemistry·Sanjin HosicAbigail N Koppes
Jan 18, 2016·Journal of Microbiological Methods·Oleg V Podgorny, Vassili N Lazarev
Feb 10, 2016·Biomicrofluidics·Jaka ČemažarRafael V Davalos
Jan 14, 2016·Biomicrofluidics·Crispin SzydzikChristian Karnutsch
Mar 26, 2016·Biomicrofluidics·Md Walid Rezanoor, Prashanta Dutta
Dec 6, 2014·Electrophoresis·Mohammad R HossanPrashanta Dutta
Jun 11, 2014·Small·Roberto de la RicaMolly M Stevens
Nov 5, 2014·Electrophoresis·Xiuzhen Zhu, Yi Chen
Jun 30, 2015·Lab on a Chip·Numa CouniotDenis Flandre
May 1, 2015·Analytical and Bioanalytical Chemistry·Mahdi MohammadiJordi Sellarès
Feb 24, 2015·Bioanalysis·Fernanda Camacho-Alanis, Alexandra Ros
Feb 2, 2015·Biosensors & Bioelectronics·Xiaoliang Guo, Rong Zhu
May 22, 2016·Infectious Disease Clinics of North America·Andrea Endimiani, Michael R Jacobs
May 23, 2016·Analytical and Bioanalytical Chemistry·Mahdi MohammadiJasmina Casals-Terré
Jul 5, 2016·Biomicrofluidics·Marco A Mata-GomezSergio O Martinez-Chapa
Jul 5, 2016·Biomicrofluidics·Ezekiel O AdekanmbiSoumya K Srivastava
Jun 21, 2016·Journal of Separation Science·Bobby MathewIon Stiharu
May 11, 2016·Biotechnology Progress·William G PittAlex K Hunter
Aug 26, 2016·Electrophoresis·Rama Aravind PrabhakaranXiangchun Xuan
Nov 11, 2016·Lab on a Chip·Thoriq SalafiYong Zhang
Dec 20, 2016·Scientific Reports·Arzu ÖzbeyAli Koşar
Dec 21, 2016·The Analyst·Gabriela B AlmeidaJosé A Fracassi da Silva
Jan 24, 2017·Electrophoresis·Daniel J AllenStuart J Williams
Mar 18, 2017·Electrophoresis·Martina Viefhues, Ralf Eichhorn
Mar 23, 2017·Electrophoresis·Shigeru TadaZhiyong Qiu
Nov 9, 2017·Lab on a Chip·ChunHui WuXing Cheng
Sep 13, 2017·Biomedical Microdevices·Chunglong TuXuesong Ye
Nov 10, 2017·The Analyst·Sarah TäuberMartina Viefhues
Jun 12, 2018·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Fadi AlnaimatSaud Khashan
Nov 14, 2017·Electrophoresis·Mohammad R HossanPrashanta Dutta
Aug 23, 2018·Lab on a Chip·Mengxi WuTony Jun Huang
Nov 6, 2018·The Analyst·Mohammad PoustiJesse Greener
Oct 23, 2018·Electrophoresis·Chien-Hsuan KoXiangchun Xuan
Mar 1, 2019·Electrophoresis·Xiangchun Xuan
Sep 21, 2019·Electrophoresis·Viktor ShkolnikovChien-Hua Chen
Nov 23, 2019·Lab on a Chip·Song-I HanArum Han
Mar 15, 2020·Micromachines·Kena SongZhigang Hu
Jun 1, 2020·Electrophoresis·Mohammad Towshif RabbaniAlexandra Ros
Aug 1, 2020·Electrophoresis·Erin A Henslee
Sep 15, 2020·Lab on a Chip·Song-I HanArum Han
Feb 9, 2017·Proceedings of the National Academy of Sciences of the United States of America·Rahim EsfandyarpourRonald W Davis
May 2, 2018·Scientific Reports·Leilei ShiLeyla Esfandiari
Jan 1, 2016·Nano-micro Letters·Jingjing XuShengyong Xu
Jul 1, 2020·Lab on a Chip·Kyunghun LeeTaesung Kim
Nov 15, 2018·Micromachines·Xiang JiJie Li