Dielectrophoretic Separation of Particles Using Microfluidic Chip with Composite Three-Dimensional Electrode

Micromachines
Li ChenYanjian Liao

Abstract

Integrating three-dimensional (3D) microelectrodes on microfluidic chips based on polydimethylsiloxane (PDMS) has been a challenge. This paper introduces a composite 3D electrode composed of Ag powder (particle size of 10 nm) and PDMS. Ethyl acetate is added as an auxiliary dispersant during the compounding process. A micromachining technique for processing 3D microelectrodes of any shape and size was developed to allow the electrodes to be firmly bonded to the PDMS chip. Through theoretical calculations, numerical simulations, and experimental verification, the role of the composite 3D microelectrodes in separating polystyrene particles of three different sizes via dielectrophoresis was systematically studied. This microfluidic device separated 20-, 10-, and 5-μm polystyrene particles nondestructively, efficiently, and accurately.

References

Apr 24, 2009·Biomedical Microdevices·Swee Jin TanChwee Teck Lim
Nov 10, 2012·Analytical Chemistry·Raghavendra Devendra, German Drazer
Jan 7, 2014·Medical Engineering & Physics·Debanjan DasSoumen Das
Dec 31, 2016·Journal of Separation Science·Anas AlazzamFalah Alhammadi
Dec 12, 2018·Biomedical Microdevices·Paridhi PuriN N Sharma
Jun 27, 2019·Micromachines·Haoqing ZhangPavel Neuzil

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Citations

Jun 1, 2021·Comprehensive Reviews in Food Science and Food Safety·Zhaoda XieDa-Wen Sun

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Methods Mentioned

BETA
chip
electrophoresis
chips

Software Mentioned

COMSOL
COMSOL Multiphysics

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