Dienogest. A possible conservative approach in bladder endometriosis. Results of a pilot study

Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology
Stefano AngioniGian Benedetto Melis

Abstract

Deep endometriosis involvement of the bladder is uncommon but it is symptomatic in most of the cases. Although laparoscopic excision is very effective, some patients with no pregnancy desire require a medical approach. We performed a pilot study on the effect of a new progestin dienogest on bladder endometriosis. Six patients were treated for 12 months with dienogest 2 mg/daily. Pain, urinary symptoms, quality of life, nodule volume and side effects were recorded. During treatment, symptoms improved very quickly and the nodules exhibit a remarkable reduction in size. Dienogest may be an alternative approach to bladder endometriosis.

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Citations

Jul 15, 2015·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Stefano AngioniGian Benedetto Melis
Oct 30, 2015·Expert Opinion on Pharmacotherapy·Anita L Nelson
Sep 13, 2015·Fertility and Sterility·Simone FerreroUmberto Leone Roberti Maggiore
Jul 6, 2016·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·A PontisS Angioni
Aug 10, 2016·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Claudia TostiFelice Petraglia
Aug 22, 2016·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Nicola BerlandaPaolo Vercellini
Nov 8, 2016·Fertility and Sterility·Paolo VercelliniSilvano Bosari
Mar 4, 2017·Archives of Gynecology and Obstetrics·Pontis AlessandroAngioni Stefano
May 4, 2017·Nature Reviews. Urology·Camran NezhatLouise P King
Jul 6, 2018·Expert Opinion on Pharmacotherapy·Simone FerreroFabio Barra
Jan 11, 2019·PloS One·Nicolas BourdelMichel Canis
Jul 18, 2019·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Stefano AngioniLuigi Nappi
Sep 16, 2017·Expert Opinion on Pharmacotherapy·Laura BuggioPaolo Vercellini
Jun 20, 2016·Hormone Molecular Biology and Clinical Investigation·Kah Teik ChewAbdul Ghani Nur Azurah
Jun 28, 2018·Drugs·Simone FerreroUmberto Leone Roberti Maggiore
Jan 6, 2021·The Journal of Obstetrics and Gynaecology Research·Tetsuya HirataYutaka Osuga
Aug 19, 2021·Reviews in Endocrine & Metabolic Disorders·Silvia VannucciniFelice Petraglia

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