PMID: 3756804Oct 15, 1986Paper

Diet and breast cancer in causation and therapy

Cancer
E L WynderL A Cohen

Abstract

The major macronutrient associated with increased breast cancer risk is dietary fat. Evidence for this association is based on epidemiologic, clinical, and laboratory animal studies. In addition, there is suggestive epidemiologic evidence that differences in postmastectomy survival rates in Japan and the United States may be attributable to differences in dietary fat intake. The importance of the type of fat consumed, as well as its amount, has emerged as an issue of major importance. Some oils, including those rich in monounsaturates, medium chain fatty acids, or omega-3 (n-3) fatty acids appear to lack tumor-promoting effects despite their presence in the diet at high levels. Possible mechanisms by which dietary fat may exert its effects could be either direct or indirect. Direct mechanisms involve dietary modification of membrane structure and function; indirect mechanisms involve alterations in the endocrine system, and/or the metabolism of essential fatty acids to biologically active eicosanoids such as prostaglandins, and suppression of immune responses. Dietary guidelines and dietary intervention trials for the primary and secondary prevention of breast cancer are discussed.

References

Nov 1, 1978·Archives of Internal Medicine·K A AldingerN A Samaan
Nov 1, 1979·Prostaglandins and Medicine·B R CulpW E Lands
Dec 1, 1975·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·D Y WangJ L Hayward
Apr 15, 1978·International Journal of Cancer. Journal International Du Cancer· Thein-Hlaing, Thein-Maung-Myint
Nov 1, 1979·Proceedings of the Society for Experimental Biology and Medicine·S H WaxlerS L Beal
Jun 1, 1978·American Journal of Epidemiology·N W ChoiA Kelly
Dec 1, 1978·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R D BulbrookJ L Hayward
May 1, 1975·Proceedings of the Society for Experimental Biology and Medicine·P C ChanL A Cohen
Oct 1, 1977·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·M K JonesG I Dyer
Jan 1, 1976·Acta Medica Scandinavica·H O BangN Hjøorne
Oct 11, 1975·Journal of the National Cancer Institute·E Fasal, R S Paffenbarger
Sep 1, 1985·The Journal of Clinical Endocrinology and Metabolism·J P DeslypereA Vermeulen
Jul 1, 1985·The American Journal of Clinical Nutrition·B J Howie, T D Shultz
Oct 1, 1985·European Journal of Cancer & Clinical Oncology·P HillF Kasumi
Mar 16, 1974·Lancet·H G KwaF J Cleton
Sep 1, 1974·Journal of the National Cancer Institute·B E HendersonM C Pike
Aug 15, 1974·International Journal of Cancer. Journal International Du Cancer·F de Waard, E A Baanders-van Halewijn
Sep 1, 1974·Journal of the National Cancer Institute·K Stavraky, S Emmons
Dec 5, 1974·The New England Journal of Medicine·L E DickinsonJ B Brown
Nov 9, 1974·British Medical Journal·S FranksH S Jacobs
May 15, 1972·International Journal of Cancer. Journal International Du Cancer·A S MorrisonS Yuasa
Jan 1, 1974·Journal of the National Cancer Institute·P C Chan, L A Cohen
May 1, 1974·Cancer·R G WilsonK Griffiths
Aug 1, 1971·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·B RavniharJ Lindtner
May 15, 1969·International Journal of Cancer. Journal International Du Cancer·V G ValaorasA Polychronopoulou
Aug 1, 1984·Journal of the National Cancer Institute·R A KarmaliC Fuchs
May 21, 1983·Lancet·R J Wurtman
Jul 1, 1980·Prostaglandins and Medicine·R A Karmali
Mar 15, 1984·The New England Journal of Medicine·W C Willett, B MacMahon
Apr 2, 1983·British Medical Journal·L J Kinlen
May 1, 1984·The American Journal of Clinical Nutrition·P HillE L Wynder
Jan 1, 1984·Nutrition and Cancer·K K Carroll, L M Braden
Oct 1, 1984·European Journal of Cancer & Clinical Oncology·D P RoseE L Wynder
Apr 1, 1984·British Journal of Cancer·D M WatsonW R Miller
Apr 1, 1983·Environmental Health Perspectives·T L Dao, P C Chan
Nov 1, 1982·The American Journal of Clinical Nutrition·A C Bach, V K Babayan

❮ Previous
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Citations

Dec 1, 1995·Mutation Research·D C Skegg
Jul 12, 2005·Progress in Biophysics and Molecular Biology·Sébastien JudéJean-Yves Le Guennec
Jan 29, 2003·The Journal of Nutritional Biochemistry·Hilda ChamrasJohn A. Glaspy
Jan 1, 1990·Annals of the New York Academy of Sciences·J B Westin, E Richter
Jul 15, 1990·International Journal of Cancer. Journal International Du Cancer·L J VattenE B Løken
Sep 1, 1991·Seminars in Surgical Oncology·L Sclafani
Sep 3, 2009·Annals of the New York Academy of Sciences·Ji-Yoon KimYoo Kyoung Park
Jul 1, 1990·Current Problems in Pediatrics·C L Kien
Jul 1, 1997·Journal of the American Dietetic Association·J H Weisburger
Jun 1, 1995·Prostaglandins, Leukotrienes, and Essential Fatty Acids·M NoguchiT Sasaki
Nov 1, 1995·Prostaglandins, Leukotrienes, and Essential Fatty Acids·M NoguchiT Sasaki
Jan 1, 1992·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·I L CrightonI E Smith
Jan 1, 1990·Diabetes Research and Clinical Practice·M Kimura
Jul 1, 1987·Preventive Medicine·E L Wynder
Aug 1, 1993·Seminars in Oncology Nursing·P E Smith
Feb 19, 2015·Critical Reviews in Food Science and Nutrition·Sarah F BrennanMarie M Cantwell
Oct 8, 1999·Journal of the American College of Nutrition·M Lipkin, H L Newmark
Jan 1, 1992·Nutrition and Cancer·S KyogokuI Hirohata
Sep 16, 2008·Nutrition and Cancer·W Elaine Hardman, Gabriela Ion
Jan 1, 1989·Breast Cancer Research and Treatment·F S ShoferL T Glickman
Jun 4, 1997·Journal of the National Cancer Institute·E L WynderG Blackburn
Mar 1, 1991·Cancer Causes & Control : CCC·J X XieH Kesteloot
Oct 1, 1992·Lipids·D P Rose, J M Connolly
May 1, 1991·Breast Cancer Research and Treatment·L Le Marchand
Mar 25, 1997·Breast Cancer : the Journal of the Japanese Breast Cancer Society·D P Rose
Jul 31, 1997·Breast Cancer : the Journal of the Japanese Breast Cancer Society·M NoguchiK Miwa
Aug 1, 1993·Journal of the American College of Nutrition·E Barrett-Connor, N J Friedlander
Jun 13, 1998·Nutrition Reviews·A H LichtensteinS L Booth
Aug 31, 2004·The Journal of Nutrition·Huseyin Aktas, Jose A Halperin
Jan 1, 1990·Medical Oncology and Tumor Pharmacotherapy·D P Rose, J M Connolly

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