PMID: 8952552Dec 15, 1996Paper

Diet and exercise regimens to improve breast carcinoma prognosis

Cancer
B A Stoll

Abstract

Clinical studies agree that obesity worsens the prognosis of breast carcinoma in both pre- and postmenopausal women. There is considerable evidence that free estrogen levels are raised in obese women, especially in those with abdominal (visceral) obesity and hyperinsulinemic insulin resistance. It has been postulated that estrogen may synergize with the concomitants of hyperinsulinemia in stimulating breast carcinoma growth. Reduction of estrogen and insulin levels may slow this growth. A current clinical trial in the U.S. is examining the effect of dietary fat reduction on recurrence and survival rates after primary treatment of early stage breast carcinoma in postmenopausal women. Recent research suggests that a high fiber/fat ratio in the diet and regular physical exercise may help to reduce estrogen and insulin levels. Regular exercise may also help to maintain long term weight loss. A second-generation trial is proposed of a high fiber, low fat diet associated with regular physical exercise in women with early breast carcinoma. Changes in circulating levels of estrogen and insulin will be monitored in relation to timing of tumor recurrence and second primary breast carcinoma rates. Weight and fat distribution will be monit...Continue Reading

References

Oct 21, 1992·International Journal of Cancer. Journal International Du Cancer·P F BruningW J Nooijen
Dec 1, 1992·Diabetes Care·M D Davis
Sep 1, 1992·The Journal of Steroid Biochemistry and Molecular Biology·R B DicksonM E Lippman
Mar 1, 1992·The Journal of Steroid Biochemistry and Molecular Biology·T ThorsenA Aakvaag
Jul 15, 1992·Journal of the National Cancer Institute·L H KushiA R Folsom
May 18, 1991·Lancet·H P LeeN E Day
Apr 3, 1991·Journal of the National Cancer Institute·L A CohenD P Rose
Jan 1, 1992·Annals of Internal Medicine·R T SenieD W Kinne
Feb 15, 1992·The American Journal of Cardiology·R J BarnardS B Inkeles
Jun 19, 1991·International Journal of Cancer. Journal International Du Cancer·D ZaridzeS W Duffy
Apr 4, 1990·Journal of the National Cancer Institute·G R HoweT Rohan
May 15, 1990·International Journal of Cancer. Journal International Du Cancer·P Van 't VeerF Sturmans
Jan 1, 1990·Scandinavian Journal of Clinical and Laboratory Investigation. Supplementum·E A Stein
Nov 15, 1990·International Journal of Cancer. Journal International Du Cancer·S KyogokuA Horie
Dec 19, 1990·Journal of the National Cancer Institute·L M Berstein
Feb 1, 1990·Annals of Internal Medicine·D V SchapiraC E Cox
Feb 21, 1990·Journal of the National Cancer Institute·R Ballard-BarbashW E Helsel
Nov 15, 1989·International Journal of Cancer. Journal International Du Cancer·J M IscovichJ M Kaldor
Jan 1, 1986·Nutrition and Cancer·T D Shultz, B J Howie
Sep 1, 1988·Preventive Medicine·J C Mohle-BoetaniR S Paffenbarger
Sep 15, 1988·International Journal of Cancer. Journal International Du Cancer·J R HebertE L Wynder
Jan 1, 1986·Diabetes/metabolism Reviews·V A KoivistoR A DeFronzo
Jun 1, 1987·The Journal of Clinical Endocrinology and Metabolism·C LongcopeJ Warram
Dec 16, 1982·The New England Journal of Medicine·B R GoldinM N Woods
May 1, 1981·Cancer·P I TartterA H Aufses
Jan 18, 1995·Journal of the National Cancer Institute·A TrichopoulouD Trichopoulos
Jan 1, 1995·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·E ToropainenK Syrjänen
Aug 12, 1995·BMJ : British Medical Journal·A M Prentice, S A Jebb
Apr 1, 1993·Neuroendocrinology·P J JenkinsA Grossman
Jan 1, 1994·Nutrition and Cancer·M J MessinaS Barnes
Dec 1, 1993·Diabetes Care·P Z Zimmet
Jan 15, 1994·International Journal of Cancer. Journal International Du Cancer·P A Baghurst, T E Rohan
Jan 1, 1993·Nutrition and Cancer·F LeviE Negri
Jan 1, 1993·Cancer Causes & Control : CCC·T E RohanA B Miller
Jan 1, 1993·Annual Review of Public Health·D P Rose
Jan 1, 1993·Diabetes Care·R M CowettP L Ogburn
Jan 1, 1996·Breast Cancer Research and Treatment·B A Stoll

❮ Previous
Next ❯

Citations

Jul 2, 2002·Journal of Consulting and Clinical Psychology·Barbara L Andersen
Jan 26, 2008·International Journal of Medical Sciences·Marco ValentiCorrado Ficorella
May 12, 2001·The Breast Journal·Basil A. Stoll
Jun 17, 1998·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·I Thune
Feb 19, 2015·Critical Reviews in Food Science and Nutrition·Sarah F BrennanMarie M Cantwell
Sep 13, 2001·ANZ Journal of Surgery·A HalderD A Watters
Jun 4, 1997·Journal of the National Cancer Institute·E L WynderG Blackburn
Jun 1, 2000·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·B A Stoll

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.