PMID: 6538617Jan 1, 1984Paper

Diet and serum sex hormones in healthy men

Journal of Steroid Biochemistry
E K HämäläinenP Pietinen

Abstract

The possible effect of dietary fat content and the ratio of polyunsaturated to saturated fatty acids (P/S-ratio) on serum sex hormones was studied in 30 healthy male volunteers. The customary diet of the subjects, which supplied 40% of energy as fat (mainly from animal sources, P/S-ratio 0.15) was replaced for a 6 weeks period by a practically isocaloric experimental diet containing significantly less fat (25% of energy) with a higher P/S-ratio (1.22) and other environmental factors were stabilized. Serum testosterone and 4-androstenedione decreased from 22.7 +/- 1.1 nmol/l to 19.3 +/- 1.2 nmol/l, (SEM, P less than 0.001) and from 4.6 +/- 0.2 nmol/l to 4.3 +/- 0.2 nmol/l (SEM, P less than 0.01), respectively. These changes were paralleled by a reduction in serum free (non-protein bound) testosterone (P less than 0.01) suggesting a possible change in biological activity. During the low fat period a significant negative correlation between serum prolactin and androgens was observed. All the changes in androgen levels were reversible. With the exception of a small but non-significant decrease in serum estradiol-17 beta, the other hormone parameters were practically unaffected by the dietary manipulation. Our results indicate that ...Continue Reading

References

Aug 1, 1975·Journal of Chronic Diseases·I T Higgins
Oct 9, 1976·Lancet·P Hill, F Wynder
Dec 1, 1979·Atherosclerosis·A NordøyD Thelle
Nov 1, 1977·Clinical Pharmacology and Therapeutics·T C Campbell
Dec 1, 1977·The Journal of Clinical Endocrinology and Metabolism·A R GlassR L Atkinson
Mar 1, 1977·Clinics in Endocrinology and Metabolism·M O Thorner
Jan 1, 1978·The Journal of Clinical Endocrinology and Metabolism·C LongcopeS E Fineberg
Jul 1, 1975·The Journal of Clinical Endocrinology and Metabolism·S R SmithC J Migeon
Nov 1, 1977·Clinical Pharmacology and Therapeutics·J Fishman, H L Bradlow
Jun 1, 1975·The Journal of Clinical Endocrinology and Metabolism·R T RubinK M Pirke
Jun 1, 1967·The Journal of Clinical Endocrinology and Metabolism·R G WielandG J Hamwi
Dec 1, 1973·British Journal of Urology·R J ShearerJ D Fergusson
Oct 1, 1974·Journal of Steroid Biochemistry·P Goddard, M J Hill
Jan 1, 1973·Journal of the National Cancer Institute·B MacMahonJ Brown
Feb 1, 1973·British Journal of Cancer·B S Drasar, D Irving
May 1, 1973·Journal of the National Cancer Institute·K Akazaki, G N Stemmerman
Aug 1, 1971·Cancer·E L WynderW F Whitmore
Nov 1, 1971·The Journal of Clinical Endocrinology and Metabolism·A VermeulenL Verdonck
Nov 1, 1981·Scandinavian Journal of Clinical and Laboratory Investigation·E W BerginkT Pyörälä
Sep 30, 1982·The New England Journal of Medicine·C EhnholmP Puska
Dec 16, 1982·The New England Journal of Medicine·B R GoldinM N Woods
Oct 1, 1982·Scandinavian Journal of Clinical and Laboratory Investigation·E Hämäläinen
Sep 1, 1980·Scandinavian Journal of Clinical and Laboratory Investigation·K Kuoppasalmi
Oct 1, 1981·Metabolism: Clinical and Experimental·B ZumoffD K Fukushima
Nov 1, 1981·The American Journal of Cardiology·J GutaiA Caggiula
May 1, 1980·The American Journal of Clinical Nutrition·P HillP Helman
Mar 1, 1980·Journal of Steroid Biochemistry·P JärvenpääH Adlercreutz
Oct 1, 1980·Metabolism: Clinical and Experimental·H K KleyH L Krüskemper
Feb 1, 1995·Obstetrical & Gynecological Survey·J BornsteinH Abramovici

❮ Previous
Next ❯

Citations

Jun 27, 2002·Current Urology Reports·I Yip, N Duran
Jan 14, 1998·Urology·W R FairW Heston
Jan 20, 2004·Medical Hypotheses·Li-Qiang QinAkio Sato
Jul 3, 1998·Critical Reviews in Oncology/hematology·M A MooreH Tsuda
Apr 15, 2004·Urologic Oncology·Ian M ThompsonBetsy Higgins
Dec 1, 2000·Nutrition Research Reviews·N E Allen, T J Key
Jan 1, 1997·Nutrition and Cancer·J SlavinL Marquart
Jan 1, 1994·Critical Reviews in Food Science and Nutrition·L U Thompson
Nov 29, 2008·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Charles P Lambert
Mar 10, 1999·Journal of the National Cancer Institute·L N KolonelR V Cooney
Jun 1, 1993·British Journal of Urology·F H Schröder
Apr 1, 1991·Journal of Clinical Periodontology·A O Ojanotko-HarriL A Sewón
Apr 27, 2004·Sports Medicine·Charles P LambertWilliam J Evans
May 28, 2014·Journal of the International Society of Sports Nutrition·Eric R HelmsPeter J Fitschen
Aug 30, 2008·Nutrition Reviews·Anne-Sophie MorissetAndré Tchernof
Dec 24, 2014·Nutrients·Katie M Di Sebastiano, Marina Mourtzakis
Jul 8, 2015·Clinical Genitourinary Cancer·Lara HilalAli Shamseddine
Dec 17, 2004·Obesity Research·Jesse RothC J Segal-Isaacson
Sep 21, 2007·Molecular Nutrition & Food Research·Eduard EscrichMontserrat Solanas
Sep 1, 1990·Metabolism: Clinical and Experimental·A W MeikleM P McMurry
Jul 12, 2005·Pharmacology, Biochemistry, and Behavior·Monica L AndersenSergio Tufik
Jun 11, 1999·The Urologic Clinics of North America·I YipW Aronson
May 31, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Simon Wilkinson, Gerald W Chodak
Nov 1, 1994·Cancer·L G FordB S Kramer
Oct 23, 2004·International Journal of Cancer. Journal International Du Cancer·Ries KranseFritz H Schröder
Jul 22, 2010·Nature Reviews. Urology·Vasundara Venkateswaran, Laurence H Klotz
Mar 3, 2005·The Journal of Clinical Endocrinology and Metabolism·Christina WangRonald S Swerdloff
Jan 4, 2007·International Journal of Urology : Official Journal of the Japanese Urological Association·Domenico PreziosoKeith Griffiths
Jan 1, 1990·Annals of the New York Academy of Sciences·H Adlercreutz
Jul 10, 2007·The Journal of Clinical Endocrinology and Metabolism·Christina WangRonald Swerdloff
Aug 26, 2000·The Journal of Nutrition·S JayapalanH M Aukema
Mar 20, 2019·Endocrine Reviews·Jean-Marc KaufmanIlpo Tapani Huhtaniemi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.