Diet and supplements in cancer prevention and treatment: Clinical evidences and future perspectives

Critical Reviews in Oncology/hematology
Claudio VernieriFilippo de Braud

Abstract

In recent years, calorie-restricted dietary regimens and compounds such as vitamins, curcumin, green tea extracts and omega-3 fatty acids have attracted attention for their potential anticancer effects. While definitive conclusions cannot be drawn in this field, many patients adopt complementary antitumor therapies aiming to improve efficacy or reduce toxicity of chemotherapy, with uncertain benefits and the risk of additional toxicities or antagonistic interactions with standard therapies. In this manuscript, we review the different levels of available evidence to suggest or discourage specific dietary changes or supplement use in the context of cancer prevention, reduction of tumor recurrences and survival prolongation in advanced cancers. Preventing or treating obesity, as well as adhering to healthy dietary patterns, should be recommended to both the general population and cancer survivors because they are convincingly associated with reduced risk of primary or second cancers and, in some cases, with reduced cancer recurrences. On the contrary, the role of specific interventions or supplements in patients with advanced malignancies is much more uncertain and actually a highly debated topic. With some exceptions, such as mel...Continue Reading

Citations

Jun 12, 2018·Journal of Pineal Research·Annia Galano, Russel J Reiter
Nov 10, 2018·Journal of Medicinal Food·Cleber da Silveira TorresHaydee Maria Moreira
Mar 11, 2020·Expert Review of Clinical Pharmacology·Edward R Sauter
Nov 19, 2018·Clinical & Experimental Metastasis·Jonathan P Sleeman
Apr 1, 2020·Journal of Cancer Research and Clinical Oncology·Omar Abdel-RahmanSheryl Koski
Jan 5, 2019·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·J BayoA Santaballa
Dec 6, 2018·Nutrients·Javier AmézagaItziar Tueros
Jun 2, 2020·American Journal of Lifestyle Medicine·Dee W EdingtonAlyssa B Schultz
Oct 16, 2020·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Noël M ArringLillian M Nail
May 16, 2020·Cancer Cell·Mylène Tajan, Karen H Vousden
Apr 1, 2021·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Claudio VernieriFilippo de Braud
Sep 14, 2021·Nutrition and Cancer·Khrystyna ZhurakivskaMonica Emanuelli

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