The fields of immunology, microbiology, nutrition and metabolism are rapidly converging. Here we expand on a diet-microbiota model as the basis for the greater incidence of asthma and autoimmunity in developed countries.
Associated Clinical Trials
Phagocytosis, peritoneal influx, and enzyme activities in peritoneal macrophages from germfree, conventional, and ex-germfree mice.
Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation.
Reduced dietary intake of carbohydrates by obese subjects results in decreased concentrations of butyrate and butyrate-producing bacteria in feces
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-20: a multicentre prospective registration study
Changes in the composition of the human fecal microbiome after bacteriotherapy for recurrent Clostridium difficile-associated diarrhea
The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice.
Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota.
Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa.
GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects
Gut microbiota as a candidate for lifespan extension: an ecological/evolutionary perspective targeted on living organisms as metaorganisms
Modulation of anti-inflammatory response in lipopolysaccharide stimulated human THP-1 cell line and mouse model at gene expression level with indigenous putative probiotic lactobacilli
Effects of three strains of intestinal autochthonous bacteria and their extracellular products on the immune response and disease resistance of common carp, Cyprinus carpio
A fresh look at the hygiene hypothesis: how intestinal microbial exposure drives immune effector responses in atopic disease
Effect of purified β-glucans derived from Laminaria digitata, Laminaria hyperborea and Saccharomyces cerevisiae on piglet performance, selected bacterial populations, volatile fatty acids and pro-inflammatory cytokines in the gastrointestinal tract of pigs
Stachyose-enriched α-galacto-oligosaccharides regulate gut microbiota and relieve constipation in mice
Macrophage immunomodulating and antitumor activities of polysaccharides isolated from Agaricus bisporus white button mushrooms
Specific dietary oligosaccharides increase Th1 responses in a mouse respiratory syncytial virus infection model.
Particular characteristics of allergic symptoms in tropical environments: follow up to 24 months in the FRAAT birth cohort study.
Restricting microbial exposure in early life negates the immune benefits associated with gut colonization in environments of high microbial diversity
Midgut microbiota of the malaria mosquito vector Anopheles gambiae and interactions with Plasmodium falciparum infection.
Early-life environmental variation affects intestinal microbiota and immune development in new-born piglets
Heat Shock Proteins: Intestinal Gatekeepers that Are Influenced by Dietary Components and the Gut Microbiota
Immune modulating capability of two exopolysaccharide-producing Bifidobacterium strains in a Wistar rat model
Glycerol supplementation enhances the protective effect of dietary FloraMax-B11 against Salmonella Enteritidis colonization in neonate broiler chickens
Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.