Dietary bioaccumulation of perfluorophosphonates and perfluorophosphinates in juvenile rainbow trout: evidence of metabolism of perfluorophosphinates

Environmental Science & Technology
Holly LeeScott A Mabury

Abstract

The perfluorophosphonates (PFPAs) and perfluorophosphinates (PFPiAs) are high production volume chemicals that have been observed in Canadian surface waters and wastewater environments. To examine whether their occurrence would result in contamination of organisms in aquatic ecosystems, juvenile rainbow trout (Oncorhynchus mykiss) were separately exposed to a mixture of C6, C8, and C10 monoalkylated PFPAs and a mixture of C6/C6, C6/C8, and C8/C8 dialkylated PFPiAs in the diet for 31 days, followed by 32 days of depuration. Tissue distribution indicated preferential partitioning to blood and liver. Depuration half-lives ranged from 3 to 43 days and increased with the number of perfluorinated carbons present in the chemical. The assimilation efficiencies (α, 7-34%) and biomagnification factors (BMFs, 0.007-0.189) calculated here for PFPAs and PFPiAs were lower than those previously observed for the perfluorocarboxylates (PFCAs) and perfluorosulfonates (PFSAs) in the same test organism. Bioaccumulation was observed to decreased in the order of PFSAs > PFCAs > PFPAs of equal perfluorocarbon chain length and was dependent on the charge of the polar headgroup. Bioaccumulation of the PFPiAs was observed to be low due to their rapid el...Continue Reading

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Citations

Oct 1, 2013·Journal of Hazardous Materials·Dandan LiuPedro J Alvarez
Sep 26, 2013·Environmental Science & Technology·Leo W Y Yeung, Scott A Mabury
Oct 16, 2013·Environment International·Jinxia Liu, Sandra Mejia Avendaño
Oct 12, 2013·Environmental Toxicology and Chemistry·Jonathan W MartinDerek C G Muir
Feb 23, 2017·Environmental Science & Technology·Holly Lee, Scott A Mabury
Oct 9, 2018·Environmental Toxicology and Chemistry·Elena NilsenHeiko L Schoenfuss
Jun 5, 2020·Environmental Science. Processes & Impacts·Ian T CousinsZhanyun Wang
Jul 3, 2021·International Journal of Molecular Sciences·Dario Savoca, Andrea Pace
Oct 24, 2017·Environmental Science & Technology·Somrutai PoothongLine Småstuen Haug
Mar 19, 2019·Environmental Science & Technology·Haotian WangJohn C Crittenden
Nov 22, 2013·Environmental Science & Technology·Lisa A D'Agostino, Scott A Mabury

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