Dietary D-psicose reduced visceral fat mass in high-fat diet-induced obese rats

Journal of Food Science
Young-Mee ChungChi Hye Park

Abstract

D-Psicose, a C-3 epimer of D-fructose, has shown promise in reducing body fat accumulation in normal rats and plasma glucose level in genetic diabetic mice. Effects of D-psicose on diet-induced obesity are not clearly elucidated, and we investigated food intake, body weight, and fat accumulation in rats fed high-fat (HF) diet. Sprague-Dawley rats became obese by feeding HF diet for 4 wk, and were assigned either to normal or HF diet supplemented with or without D-psicose, sucrose, or erythritol for 8 wk. Changing HF to normal diet gained less body weight and adipose tissue due to different energy intake. D-psicose-fed rats exhibited lower weight gain, food efficiency ratio, and fat accumulation than erythritol- and sucrose-fed rats. This effect was more prominent in D-psicose-fed rats with normal diet than with HF diet, suggesting combination of psicose and calorie restriction further reduced obesity. There was no difference in serum cholesterol/high-density lipoprotein (HDL)-C and low-density lipoprotein (LDL)-C/HDL-C ratios between D-psicose group and other groups. Liver weight in 5% psicose group with normal diet was higher than in other groups, but histopathological examination did not reveal any psicose-related change. D-P...Continue Reading

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Citations

Jul 13, 2014·Biological Trace Element Research·Mirosław KrośniakRyszard Gryboś
Oct 10, 2014·Journal of Nutritional Science and Vitaminology·Takako YamadaTatsuhiro Matsuo
Nov 13, 2014·Journal of Food Science·Siwaporn O'CharoenMasahiro Ogawa
Jun 3, 2016·Journal of Agricultural and Food Chemistry·Min-Oh ParkSang-Ho Yoo
Aug 23, 2016·Tetrahedron Letters·Liuqing WenPeng George Wang
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May 8, 2013·Bioscience, Biotechnology, and Biochemistry·Masaru OchiaiTatsuhiro Matsuo
Oct 23, 2013·International Journal of Food Sciences and Nutrition·Masaru OchiaiTatsuhiro Matsuo
Sep 20, 2017·The Journal of Veterinary Medical Science·Naohito NishiiHitoshi Kitagawa
Aug 2, 2017·Journal of Nutritional Science and Vitaminology·Masaru OchiaiTatsuhiro Matsuo
Mar 3, 2020·Frontiers in Bioengineering and Biotechnology·Suwei JiangJingjing Liu
Nov 6, 2020·Nutritional Neuroscience·Wasana PratchayasakulSiriporn C Chattipakorn
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Jan 6, 2022·Journal of Food Biochemistry·Michael J HaasArshag D Mooradian

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