Dietary Factors Promoting Brown and Beige Fat Development and Thermogenesis

Advances in Nutrition
Meshail OklaSoonkyu Chung

Abstract

Brown adipose tissue (BAT) is a specialized fat tissue that has a high capacity to dissociate cellular respiration from ATP utilization, resulting in the release of stored energy as heat. Adult humans possess a substantial amount of BAT in the form of constitutively active brown fat or inducible beige fat. BAT activity in humans is inversely correlated with adiposity, blood glucose concentrations, and insulin sensitivity; this suggests that strategies aimed at BAT-mediated bioenergetics are an attractive therapeutic target in combating the continuing epidemic of obesity and diabetes. Despite advances in knowledge regarding the developmental lineage and transcriptional regulators of brown and beige adipocytes, our current understanding of environmental modifiers of BAT thermogenesis, such as diet, is limited. In this review, we consolidated the latest research on dietary molecules that may serve to promote BAT thermogenesis. Here, we summarized the thermogenic function of selected phytochemicals (e.g., capsaicin, resveratrol, curcumin, green tea, and berberine), dietary fatty acids (e.g., fish oil and conjugated linoleic acids), and all-trans retinoic acid, a vitamin A metabolite. We also delineated the proposed mechanisms where...Continue Reading

Citations

Feb 27, 2018·Current Hypertension Reports·Mohammad G Saklayen
Jul 30, 2019·Advances in Nutrition·Ziye XuTizhong Shan
Jun 25, 2019·Current Protein & Peptide Science·Wenjing YouTizhong Shan
Feb 1, 2020·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Zilun LiSifan Chen
Jun 1, 2020·Journal of Physiology and Biochemistry·María J Moreno-Aliaga, Francesc Villarroya
Jun 1, 2018·The Journal of Endocrinology·Gisela Helfer, Qing-Feng Wu
Jul 29, 2020·Cell Death & Disease·Wenjing YouTizhong Shan
Mar 10, 2018·Adipocyte·Jens LundLotte Lauritzen
Jun 21, 2019·Journal of Molecular Cell Biology·Wen MengFeng Liu
Apr 3, 2020·Nature Reviews. Endocrinology·Rodrigo San-CristobalJosé Alfredo Martínez
Dec 5, 2019·International Journal of Molecular Sciences·Silvia Lorente-CebriánHeriberto Castro
Jul 19, 2019·Frontiers in Endocrinology·Liyuan ZhouMingqun Deng
May 7, 2020·Frontiers in Endocrinology·Masayuki SaitoYuko Okamatsu-Ogura
Dec 20, 2019·Journal of Physiology and Biochemistry·Marta Fernández-GalileaMaria J Moreno-Aliaga
Nov 16, 2017·Oxidative Medicine and Cellular Longevity·Yueshui ZhaoZhangang Xiao
Sep 3, 2020·International Journal of Molecular Sciences·Alina Kuryłowicz, Monika Puzianowska-Kuźnicka
Jan 4, 2021·Veterinary Medicine and Science·Ronny LesmanaUnang Supratman
Dec 2, 2020·Molecular Nutrition & Food Research·Na XuXiaochun Wan
Aug 3, 2019·European Journal of Medicinal Chemistry·Lucia BiasuttoMario Zoratti
Aug 12, 2019·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Hanbing LiLinghuan Li
Dec 5, 2020·Oxidative Medicine and Cellular Longevity·Xueying LiuChuangpeng Shen
Nov 13, 2020·Oxidative Medicine and Cellular Longevity·Mona AlonaziAbir Ben Bacha
Mar 3, 2020·Molecular and Cellular Endocrinology·Thamiris de SouzaMarta Citelli
Sep 30, 2018·Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids·Rong FanSoonkyu Chung
Feb 26, 2021·The Journal of Biological Chemistry·Jin-Seon YookSoonkyu Chung
Jun 22, 2020·The Journal of Nutritional Biochemistry·Anaysa Paola BolinRosemari Otton
Mar 30, 2021·Frontiers in Endocrinology·Anna-Claire PilkingtonUmesh D Wankhade
Oct 1, 2020·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Lucas Jurado-FasoliJonatan R Ruiz
Jun 3, 2021·International Journal of Molecular Sciences·Bruna B BrandãoAtefeh Rabiee
Jun 26, 2021·Advances in Nutrition·Danielle L ÁvilaJacqueline I Alvarez-Leite

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved