PMID: 9430610Jan 31, 1998Paper

Dietary fructooligosaccharides prevent osteopenia after gastrectomy in rats

The Journal of Nutrition
A OhtaT Sakata

Abstract

Postgastrectomy osteopenia is observed generally in humans. Fructooligosaccharides increase the absorption of calcium from the large intestine of healthy rats. Thus, we have examined whether they stimulate calcium absorption and prevent osteopenia in rats following total gastrectomy. Rats were subjected to either a sham surgical operation or Billoth II gastrectomy. Seven rats from each surgical treatment group were fed a control diet, and another seven rats of each treatment group were fed a diet containing fructooligosaccharides (75 g/kg diet) for 4 wk. For 5 d each week, feces were collected, and the calcium and phosphorus contents were measured for calculation of the absorption of these minerals. At the end of the experiment, the rats were killed and bones were collected. The net calcium absorption, calcium content and bone mineral density of the femur and tibia in gastrectomized rats fed the control diet were significantly less than those in sham-operated rats fed control diet. The net calcium absorption in rats fed the fructooligosaccharides diet was greater than that in rats fed control diet. Moreover, dietary fructooligosaccharides prevented the decrease in the calcium content and bone mineral density in gastrectomized r...Continue Reading

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Citations

May 30, 2003·Experimental Biology and Medicine·Marlena C KrugerLinda M Schollum
Sep 19, 2009·Journal of Nutritional Science and Vitaminology·Yumi NakayaAtsutane Ohta
Jan 11, 2012·Bioscience, Biotechnology, and Biochemistry·Hiroya EndoJinichiro Koga
Dec 5, 2009·Scandinavian Journal of Gastroenterology·Pentti Sipponen, Matti Härkönen
Jan 1, 2010·Annual Review of Food Science and Technology·R A Rastall
Sep 11, 2012·Journal of Clinical Biochemistry and Nutrition·Yoshifumi KimiraMariko Uehara
Feb 7, 2001·The American Journal of Clinical Nutrition·K E Scholz-AhrensJ Schrezenmeir
Jul 14, 2006·Menopause : the Journal of the North American Menopause Society·Latha DevareddyBahram H Arjmandi
May 6, 2019·Bioscience, Biotechnology, and Biochemistry·Daiki SuehiroTakashi Hayakawa
Apr 17, 2001·Bioscience, Biotechnology, and Biochemistry·K SakaiA Ohta
Jul 27, 2011·Revista do Colégio Brasileiro de Cirurgiões·Elisvânia Freitas dos SantosCelio Kenji Miyasaka
Jun 11, 2014·Critical Reviews in Food Science and Nutrition·Vandana BaliReeba Panesar
Jun 22, 2018·Nutrients·Mariane Moreira Ramiro do CarmoElisvânia Freitas Dos Santos
Sep 18, 2008·Acta Cirúrgica Brasileira·Elisvânia Freitas Dos SantosCelio Kenji Miyasaka
Jul 8, 1999·The Journal of Nutrition·J L Greger

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