Abstract
Glycemic index (GI) and glycemic load (GL) influence postprandi al glucose concentrations and insulin responses. This study aims to ascertain the connection between GI, GL, and carotid atherosclerotic stenosis and cardiovascular disease (CVD) risk factors. A total of 669 patients with ischemic stroke within 7 days were enrolled. GI and GL were assessed with a validated food frequency questionnaire from patients. Computed tomography angiography (CTA) was used for the evaluation of carotid atherosclerotic stenosis. Traditional risk factors such as total cholesterol, triglycerides, LDL-C, HDL-C, C-reactive protein, homocysteine, neutrophil to lymphocyte ratio (NLR), fasting plasma glucose, and hemoglobin A1c were measured. GI/GL and its association with CVD risk factors and carotid stenosis were explored with Spearman analysis and multivariable logistic regression, respectively. The prevalence of carotid stenosis was 63.2% of all 669 participants. The mean value of GI/GL was 49.3/137. Spearman test did not detect significant relationships between GI/GL and CVD risk factors. In multivariable regression models, GI (4th vs. 1st quartile, OR=2.11; 95% CI, 1.30-3.42) and GL (4th vs. 1st quartile, OR=1.82; 95% CI, 1.12-2.96) were observ...Continue Reading
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Citations
Aug 28, 2020·Journal of Atherosclerosis and Thrombosis·Min Yuan, Huang-Yan Zhou
Aug 28, 2020·Journal of Atherosclerosis and Thrombosis·Min PengGelin Xu
May 21, 2021·Journal of Atherosclerosis and Thrombosis·Nobuo SasakiYukihito Higashi