Dietary influences on intestinal immunity.

Nature Reviews. Immunology
Marc Veldhoen, Verena Brucklacher-Waldert

Abstract

The function of the gastrointestinal tract relies on a monolayer of epithelial cells, which are essential for the uptake of nutrients. The fragile lining requires protection against insults by a diverse array of antigens. This is accomplished by the mucosa-associated lymphoid tissues of the gastrointestinal tract, which constitute a highly organized immune organ. In this Review, we discuss several recent findings that provide a compelling link between dietary compounds and the organization and maintenance of immune tissues and lymphocytes in the intestine. We highlight some of the molecular players involved, in particular ligand-activated nuclear receptors in lymphoid cells.

References

Nov 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·L F BjeldanesC A Bradfield
Apr 29, 1997·Proceedings of the National Academy of Sciences of the United States of America·S A KliewerJ M Lehmann
Jan 6, 1999·Proceedings of the National Academy of Sciences of the United States of America·B A JanowskiD J Mangelsdorf
May 21, 1999·Science·M MakishimaB Shan
Jan 21, 2000·The Journal of Immunology : Official Journal of the American Association of Immunologists·R B ClarkS J Padula
Feb 29, 2000·The Journal of Immunology : Official Journal of the American Association of Immunologists·G Penna, L Adorini
Sep 20, 2002·The New England Journal of Medicine·Jean-Francois Bach
Oct 3, 2002·Nature Reviews. Immunology·Toby LawrenceDerek W Gilroy
Jan 14, 2003·Nature Medicine·Sean B JosephPeter Tontonoz
Jul 4, 2003·Nature·J Rodrigo MoraUlrich H Von Andrian
Feb 14, 2004·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Atsuhiro OgawaYoshihide Fujiyama
Oct 16, 2004·Immunity·Makoto IwataSi-Young Song
Dec 28, 2004·Nature Medicine·Akira HirasawaGozoh Tsujimoto
Feb 9, 2005·The American Journal of Clinical Nutrition·Loren CordainJanette Brand-Miller
Sep 2, 2005·Nature Reviews. Genetics·Sudhir Kumar
Oct 12, 2005·The Journal of Experimental Medicine·Bengt Johansson-LindbomWilliam W Agace
Jan 21, 2006·The Journal of Clinical Investigation·Roger P M SutmullerGosse J Adema
Feb 24, 2006·Nature Reviews. Immunology·Christopher K Glass, Sumito Ogawa
Sep 13, 2006·The Journal of Biological Chemistry·Jinghong WangLei Ling
Oct 20, 2006·Proceedings of the National Academy of Sciences of the United States of America·Giovanni SolinasMichael Karin
Oct 21, 2006·The Journal of Clinical Investigation·Hang ShiJeffrey S Flier
Oct 26, 2006·Nature Reviews. Immunology·Graham Devereux
Nov 18, 2006·Science·J Rodrigo MoraUlrich H von Andrian
Nov 25, 2006·The New England Journal of Medicine·Waltraud EderErika von Mutius
Dec 15, 2006·Nature·Gökhan S Hotamisligil
Jun 15, 2007·Annals of the Rheumatic Diseases·Yoav ArnsonYehuda Shoenfeld
Jul 10, 2007·The American Journal of Gastroenterology·Devendra K AmreErnest G Seidman
Jul 11, 2007·The Journal of Experimental Medicine·Cheng-Ming SunYasmine Belkaid
Aug 28, 2007·Nature Reviews. Cancer·Kristin K DeebCandace S Johnson
Oct 20, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Shelley GormanPrue H Hart

❮ Previous
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Citations

Dec 12, 2012·The British Journal of Nutrition·Béatrice GleizePatrick Borel
Aug 1, 2013·Inflammatory Bowel Diseases·Isabelle Frey-WagnerGerhard Rogler
Jun 13, 2014·Cell Communication and Signaling : CCS·Natascha Hermann-Kleiter, Gottfried Baier
Sep 23, 2014·Nature Reviews. Immunology·Allan M Mowat, William W Agace
Nov 12, 2014·International Journal of Molecular Sciences·Maria Vittoria BaroneSalvatore Auricchio
Feb 25, 2015·Journal of Immunological Methods·Rafael Pires OliveiraAna Maria Caetano Faria
Jun 2, 2016·The British Journal of Nutrition·Ruoxu DouShuji Ogino
Jun 23, 2015·Cell Metabolism·Milena Monteiro-SepulvedaEdith Brot-Laroche
Mar 13, 2016·Journal of Biochemistry·Takahiro YamadaKoji Hase
Jun 27, 2014·Amino Acids·Bin WangZhenlong Wu
May 7, 2014·Journal of the Science of Food and Agriculture·Jan van de VeldeArjen Schots
Sep 9, 2015·Frontiers in Immunology·Sara M ParigiEduardo J Villablanca
Feb 11, 2014·Journal of Immunological Methods·Andrew W GoodyearElizabeth P Ryan
Apr 24, 2015·Annals of Medicine·Leena von HertzenWillem M de Vos
Jun 21, 2014·Immunity·Alison N ThorburnCharles R Mackay
Apr 25, 2015·Nature Reviews. Immunology·Valerie JuliaDavid Dombrowicz
Jan 13, 2015·Gastroenterology·Mingyang SongAndrew T Chan
Jan 13, 2015·Gastroenterology·Herbert Tilg, Alexander R Moschen
Oct 24, 2014·Frontiers in Immunology·Verena Brucklacher-WaldertMarc Veldhoen
Feb 18, 2015·Nature Immunology·Marc Veldhoen, Henrique Veiga-Fernandes
Dec 8, 2014·Clinics and Research in Hepatology and Gastroenterology·Yuk Man Kevin LeiMaria-Luisa Alegre
Apr 5, 2016·Immunology·Michael Bscheider, Eugene C Butcher
Aug 6, 2016·Cellular and Molecular Life Sciences : CMLS·Stefanie JörgMarkus Kleinewietfeld
Mar 10, 2016·The Journal of Physiology·Gera GoverseGianluca Matteoli
Jul 20, 2016·The Journal of Experimental Medicine·Christoph WilhelmYasmine Belkaid
Apr 20, 2017·Parasite Immunology·D R Neill, R J Flynn
Jun 22, 2016·Nature Immunology·Christoph S N Klose, David Artis
Jan 11, 2017·The Journal of Immunology : Official Journal of the American Association of Immunologists·Eran BlacherEran Elinav
Jan 20, 2017·The Journal of Immunology : Official Journal of the American Association of Immunologists·Gera GoverseReina E Mebius
Jun 21, 2017·The Journal of Immunology : Official Journal of the American Association of Immunologists·Prosper N Boyaka
Sep 19, 2017·Nature Reviews. Immunology·Morten M NielsenWendy L Havran
Jul 26, 2018·European Journal of Immunology·Marc VeldhoenCristina Ferreira
Jul 30, 2017·Applied and Environmental Microbiology·Rafael J M PeixotoL Caetano M Antunes
Jun 30, 2015·Nature Medicine·Marc Veldhoen, Cristina Ferreira
May 16, 2019·Toxicological Sciences : an Official Journal of the Society of Toxicology·Christopher D Sundberg, Oliver Hankinson

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