Abstract
Several different edible oils were compared for their ability to modify eicosanoid biosynthesis following experimentally-induced myocardial ischemia and reperfusion in the rat. Two types of palm oil [neutralized, bleached, and deodorized (NBDPO) and refined, bleached, and deodorized (RBDPO)] and partially hydrogenated soybean oil (SBO) were tested against a diet supplemented with sunflower seed oil (SSO) rich in n-6 polyunsaturated fatty acids (PUFA). Fish oil (FO) rich in n-3 PUFA, with its known cardioprotective actions, served as an internal reference point for the study. Test oils were fed as a 12% (w/w) supplement for nine months before the induction of myocardial ischemia and reperfusion. Palm oil diets exerted effects indistinguishable from the SBO group against cardiac arrhythmia, which occurred following alterations to coronary blood flow. Arrhythmic potentials, as expressed by a hierarchical scale (0-9) of arrhythmia score, were: SSO, 1.5 +/- 0.5; FO, 0.9 +/- 0.4; SBO, 3.1 +/- 0.5*; NBDPO, 3.2 +/- 0.5*; RBDPO, 3.3 +/- 0.6*; *P < 0.05 vs. SSO. Following ischemia and reperfusion, both SSO and RBDPO groups tended to show an increase in myocardial prostacyclin, with the effect being more prominent in the RBDPO group (SSO,...Continue Reading
References
Jun 1, 1992·American Heart Journal·P L McLennanJ S Charnock
Mar 1, 1991·Prostaglandins, Leukotrienes, and Essential Fatty Acids·M Y AbeywardenaJ S Charnock
Jul 1, 1990·Prostaglandins, Leukotrienes, and Essential Fatty Acids·C GisingerJ A Colwell
Jan 1, 1989·Annals of the New York Academy of Sciences·P ReddannaC C Reddy
Dec 15, 1989·Biochemical Pharmacology·D R JaneroM Cardell
Oct 1, 1989·Japanese Circulation Journal·A J FuenmayorD M Winterdaal
Apr 1, 1989·Prostaglandins, Leukotrienes, and Essential Fatty Acids·J W BlankenshipR J Boucek
Feb 1, 1987·Biochemical Pharmacology·R J GryglewskiJ Swies
Aug 1, 1987·Cardiovascular Research·T KuzuyaM Tada
Sep 1, 1988·Cardiovascular Research·M J Curtis, M J Walker
Jan 1, 1986·Annals of Nutrition & Metabolism·J S CharnockP L McLennan
Jan 1, 1985·Annals of Nutrition & Metabolism·J S CharnockG R Russell
Oct 1, 1984·Biochemical Pharmacology·T TeranoS Moncada
Jun 1, 1984·Journal of Molecular and Cellular Cardiology·A S Manning, D J Hearse
Mar 1, 1984·Lipids·J S CharnockG R Russell
Jul 1, 1980·Circulation Research·S WallensteinJ L Fleiss
Jan 1, 1994·Progress in Lipid Research·J S Charnock
May 1, 1993·Cardiovascular Research·J Parratt
Feb 1, 1993·The American Journal of Clinical Nutrition·P L McLennan
Citations
Feb 4, 2006·The Journal of Membrane Biology·P L McLennan, M Y Abeywardena
Dec 7, 2005·Lipids·Glen S PattenMahinda Y Abeywardena
Apr 2, 1999·Lipids·M G MurphyR G Ackman
Oct 25, 2000·The Journal of Nutritional Biochemistry·W R LeifertE J McMurchie
Aug 23, 2001·The Journal of Nutritional Biochemistry·W R. LeifertE J. McMurchie
Nov 13, 2004·The Journal of Nutritional Biochemistry·W R LeifertE J McMurchie
Nov 13, 2004·The Journal of Nutritional Biochemistry·W R LeifertE J McMurchie
Jul 9, 2011·The British Journal of Nutrition·Ravigadevi SambanthamurthiMohd Basri Wahid
Nov 10, 2011·The British Journal of Nutrition·Peter L McLennanDaniel Raederstorff
Sep 21, 2010·Nutrition Research Reviews·D BesterJ van Rooyen
Apr 5, 2014·European Journal of Applied Physiology·Peter L McLennan
Jan 8, 2016·Nutrients·Mahinda Y AbeywardenaSoressa M Kitessa
Jan 25, 2005·Prostaglandins, Leukotrienes, and Essential Fatty Acids·A J EsterhuyseJ van Rooyen
Nov 29, 2005·Metabolism: Clinical and Experimental·Nirupa R MatthanJoseph Lau
Aug 14, 2019·The British Journal of Nutrition·Afroza FerdouseHarold M Aukema
Sep 8, 2001·Prostaglandins, Leukotrienes, and Essential Fatty Acids·M Y Abeywardena, R J Head