Dietary Modifications and Lipid Accumulation Product Are Associated with Systolic and Diastolic Blood Pressures in the Women's Health Trial: Feasibility Study in Minority Populations

Current Hypertension Reports
Alok Bhargava

Abstract

Approximately 65% of adults over 60 years in the USA are hypertensive. Poor dietary habits and sedentary lifestyles are fueling the hypertension epidemic. The effects of higher intakes of fruits and vegetables and whole-grain products on systolic and diastolic blood pressures were analyzed using data at baseline, 6 months, and 12 months on 349 and 573 subjects, respectively, in the control and intervention groups of the Women's Health Trial: Feasibility Study in Minority Populations. Models for systolic and diastolic blood pressures have been estimated using cross-sectional and longitudinal data in different settings. However, it is important to estimate comprehensive dynamic random effects models that take into account inter-relationships between systolic and diastolic blood pressures as well as the effects of dietary intakes and biomarkers for making robust inferences. There were significantly greater reductions (P < 0.05) between baseline and 12 months in systolic and diastolic blood pressures in the intervention group. Second, ratios of α-tocopherol to energy intakes were negatively and significantly associated with systolic and diastolic blood pressures in the intervention group. Third, the lipid accumulation product was p...Continue Reading

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Citations

Jun 2, 2020·The Cochrane Database of Systematic Reviews·Lee HooperC Murray Skeaff
Nov 24, 2020·Current Treatment Options in Cardiovascular Medicine·Sujana BallaFatima Rodriguez

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