PMID: 30001275DOI: 10.1249/jes.0000000000000167Jul 13, 2018Paper
Dietary Nitrate Enhances the Contractile Properties of Human Skeletal Muscle
Exercise and Sport Sciences Reviews
Andrew R Coggan, Linda R Peterson
Abstract
Dietary nitrate, a source of nitric oxide (NO), improves the contractile properties of human muscle. We present the hypothesis that this is due to nitrosylation of the ryanodine receptor and increased NO signaling via the soluble guanyl cyclase-cyclic guanosine monophosphate-protein kinase G pathway, which together increase the free intracellular Ca concentration along with the Ca sensitivity of the myofilaments themselves.
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BETA
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