Dietary nitrate reduces the O2 cost of desert marching but elevates the rise in core temperature

European Journal of Applied Physiology
Matthew R KuennenKevin Christmas

Abstract

Dietary nitrate (NO3 (-)) supplementation reduces the O2 cost of fixed-workload tasks performed in temperate environments but has not been examined in the heat. If this effect were retained it could reduce heatstroke risk in military personnel that are deployed for desert combat. Nine men completed three 45 min loaded battle marches at a standard cadence (4.83 km h(-1)/1.5 % grade) while wearing full combat gear [BDU, boots, body armor (8 kg), NBC suit] and carrying a loaded rucksack (16 kg). The 1st March (FAM) commenced in a temperate environment. The 2nd and 3rd commenced in simulated dry desert conditions (41 °C/20 % RH) and required subjects to ingest the beetroot juice equivalent of 8.4 mmol NO3 (-) (BRJ) or a NO3 (-) depleted placebo (PLA) for 6 days prior. VO2, VCO2, V E, core (T re), skin (T sk), and mean body (T b) temperatures, HR, and physiological strain index (PSI) were measured continuously. Thermal sensation, generalized discomfort, and perceived exertion (RPE) were measured at 5 min intervals. Heat storage (HS) was calculated. Blood markers of gastrointestinal permeability (TNF, Il-6, HO-1) were measured before and after exercise. VO2 in BRJ was lower than PLA from 1 to 12; 16 to 26; and 29 to 45 min of exercis...Continue Reading

References

Dec 1, 1992·Journal of Applied Physiology·W C AdamsE R Nadel
Jan 1, 1974·Physiological Reviews·L B Rowell
May 1, 1972·Journal of Applied Physiology·W Van Beaumont
Nov 1, 1993·Chest·A BouchamaM Rezeig
Aug 7, 1998·International Journal of Sports Medicine·W L Kenney
Apr 15, 1999·Respiration; International Review of Thoracic Diseases·J GonzalezH G Welch
May 1, 1964·Journal of Applied Physiology·N L RAMANATHAN
Feb 18, 2004·Military Medicine·Joseph J KnapikEverett Harman
Jun 29, 2004·European Journal of Applied Physiology·H ZhangD Wang
Jul 14, 2004·Sports Medicine·Eran HadadDaniel S Moran
Apr 21, 2005·The Journal of Clinical Investigation·Mark R DuranskiDavid J Lefer
Jan 13, 2006·American Journal of Physiology. Gastrointestinal and Liver Physiology·Karol DokladnyThomas Y Ma
Apr 8, 2006·Physiological Reviews·Stefan W RyterAugustine M K Choi
Aug 28, 2007·Journal of Science and Medicine in Sport·Mark Hargreaves
Jan 3, 2008·Nature Reviews. Drug Discovery·Jon O LundbergMark T Gladwin
Mar 8, 2008·Pharmacological Reviews·Nader G Abraham, Attallah Kappas
Dec 25, 2009·European Journal of Applied Physiology·Matthew R KuennenSuzanne M Schneider
Mar 20, 2010·American Journal of Physiology. Gastrointestinal and Liver Physiology·Christina L Ohland, Wallace K Macnaughton
May 15, 2010·Journal of Applied Physiology·Stephen J BaileyAndrew M Jones
Aug 7, 2010·Journal of Applied Physiology·Samuel N CheuvrontMichael N Sawka
Nov 13, 2010·Journal of Applied Physiology·Katherine E LansleyAndrew M Jones
Dec 15, 2010·American Journal of Physiology. Gastrointestinal and Liver Physiology·Tania MarchbankRaymond J Playford
Feb 3, 2011·Cell Metabolism·Filip J LarsenEddie Weitzberg
May 7, 2011·Ergonomics·George HavenithSvein Martini
May 27, 2011·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Matthew KuennenPope Moseley
Apr 3, 2012·Aviation, Space, and Environmental Medicine·Peter I Brown, Alison K McConnell
May 23, 2012·Journal of Strength and Conditioning Research·Yoram EpsteinYuval Heled
Jun 13, 2012·The Journal of Physiology·Andrés HernándezHåkan Westerblad
Jul 10, 2012·Journal of Applied Physiology·Evi MasscheleinPeter Hespel
Mar 26, 2013·Exercise and Sport Sciences Reviews·Matthew KuennenPope Moseley
May 4, 2013·Journal of Applied Physiology·Lee J WylieAndrew M Jones
Oct 4, 2013·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Brynmor C BreeseAndrew M Jones
Feb 5, 2014·Military Medicine·Kai PihlainenHeikki Kyröläinen
Feb 7, 2014·The American Journal of Clinical Nutrition·Filip J LarsenEddie Weitzberg
Feb 15, 2014·European Journal of Applied Physiology·Mark A Faghy, Peter I Brown
Mar 14, 2014·Medicine and Science in Sports and Exercise·Kim van WijckMartijn Poeze
Apr 1, 2014·Medicine and Science in Sports and Exercise·Georg Haider, Jonathan P Folland
May 6, 2014·Sports Medicine·Andrew M Jones
Dec 3, 2014·Journal of Thermal Biology·Nigel A S TaylorGlen P Kenny

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Citations

Apr 20, 2017·International Journal of Sports Physiology and Performance·Joseph A McQuillanAndrew E Kilding
Sep 11, 2019·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Garrett W HillMatthew R Kuennen
Apr 16, 2020·Critical Reviews in Food Science and Nutrition·H ZamaniS G J van Breda
Nov 22, 2019·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Garrett W HillMatthew R Kuennen
Oct 3, 2018·European Journal of Applied Physiology·Peter A FalgianoMatthew R Kuennen
Aug 8, 2017·Journal of Sports Sciences·Georgina L KentPeter Peeling
Jan 13, 2021·International Journal of Environmental Research and Public Health·Amanda M DumarChristopher G Ballmann

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