Dietary patterns and cardiovascular risk in postmenopausal women: Protocol of a cross-sectional and prospective study

Maturitas
Kimon StamatelopoulosIrene Lambrinoudaki

Abstract

Aging and menopause are associated with an adverse cardiometabolic profile, predisposing to cardiovascular disease. Diet may also affect their cardiometabolic risk. The aim of this study is to assess dietary habits and patterns of postmenopausal women and their association with adiposity measures, cardiometabolic parameters and subclinical atherosclerosis. The study will include two parts. The first part consists of cross-sectional evaluation of 750 postmenopausal women recruited consecutively from the Menopause Unit of an academic hospital. Dietary intake will be assessed by a food frequency questionnaire. Nutrient and food group intake will be calculated and adherence to the Mediterranean diet and other dietary patterns will be evaluated. A-priori and a-posteriori defined dietary patterns will be tested for associations with major and minor outcome measures. The second part consists of a prospective follow-up of all women recruited at baseline and re-assessment of the same variables after 3 years. Adherence to predefined or a-posteriori defined dietary patterns over these 3 years will be evaluated in association with changes in obesity indices and lipid levels, as well as in the progression of subclinical atherosclerosis. Bod...Continue Reading

Citations

Apr 25, 2020·Critical Reviews in Food Science and Nutrition·Luigi BarreaGiovanna Muscogiuri
May 22, 2020·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Aleksandar ĐogoSvetlana Vujovic

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