Dietary Patterns and Mediterranean Diet Score and Hazard of Recurrent Coronary Heart Disease Events and All-Cause Mortality in the REGARDS Study.

Journal of the American Heart Association
James M ShikanySuzanne E Judd

Abstract

Previously, we reported on associations between dietary patterns and incident acute coronary heart disease (CHD) in the REGARDS (Reasons for Geographic and Racial Differences in Stroke) study. Here, we investigated the associations of dietary patterns and a dietary index with recurrent CHD events and all-cause mortality in REGARDS participants with existing CHD. We included data from 3562 participants with existing CHD in REGARDS. We used Cox proportional hazards regression to examine the hazard of first recurrence of CHD events-definite or probable MI or acute CHD death-and all-cause mortality associated with quartiles of empirically derived dietary patterns (convenience, plant-based, sweets, Southern, and alcohol and salads) and the Mediterranean diet score. Over a median 7.1 years (interquartile range, 4.4, 8.9 years) follow-up, there were 581 recurrent CHD events and 1098 deaths. In multivariable-adjusted models, the Mediterranean diet score was inversely associated with the hazard of recurrent CHD events (hazard ratio for highest score versus lowest score, 0.78; 95% confidence interval, 0.62-0.98; PTrend=0.036). The Southern dietary pattern was adversely associated with the hazard of all-cause mortality (hazard ratio for Q...Continue Reading

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Citations

Mar 15, 2019·Circulation Research·Sebastian Brandhorst, Valter D Longo
Jul 25, 2019·Circulation·Alexander G BickUNKNOWN VA Million Veteran Program
Jan 18, 2020·International Journal of Environmental Research and Public Health·Sergey MaksimovOksana Drapkina
Oct 14, 2020·Health and Quality of Life Outcomes·Mahdi Vajdi, Mahdieh Abbasalizad Farhangi
May 7, 2021·Critical Reviews in Food Science and Nutrition·Sahar JafariAli Barzegar
Jul 1, 2021·Journal of the American Heart Association·James M ShikanySuzanne E Judd
Oct 26, 2021·Journal of the American Geriatrics Society·Neil A KellyParag Goyal

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Methods Mentioned

BETA
urine collection
coronary artery bypass

Software Mentioned

Stata
SAS
NutritionQuest

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