Dietary polyunsaturated fatty acids from flaxseed affect immune responses of dairy sheep around parturition

Veterinary Immunology and Immunopathology
Mariangela CaropreseAgostino Sevi

Abstract

The objective of the study was to characterize the immune profile of dairy ewes fed flaxseed, rich in polyunsaturated fatty acids (PUFA), around parturition. The hypothesis to be verified was that a physiological stressor, such as parturition, could be overcome with a nutritional manipulation in the diet of the animal in order to guarantee welfare of animals and to sustain their immune responses. Twenty Comisana ewes were divided in two groups (10 ewes/group), and fed a supplementation of whole flaxseed in the diet (FS group) or no supplementation (CON group). Blood samples were collected at parturition and then 7, 14, 21, 28, and 42 day post partum. Plasma samples were used to assess the humoral immune response after ovalbumin (OVA) immunization. At parturition, at 14 day, and 42 day post partum the level of plasma cytokines was assessed. The sheep showed a reduced responsiveness to OVA immunization. In FS ewes the IL-6 level remained unchanged until 14 day post partum and then significantly decreased from 14 day to 42 day post partum. IL-10 level was significantly higher in FS ewes than in CON ewes at 14 day. At parturition IL-1β level was significantly lower in FS ewes than in CON ewes and significantly decreased in both gro...Continue Reading

References

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Nov 8, 2008·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Kevin L Fritsche

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Citations

Feb 2, 2019·Animals : an Open Access Journal From MDPI·Maria Giovanna CilibertiMariangela Caroprese
Dec 11, 2019·Tropical Animal Health and Production·Arash VeshkiniAbdolreza Salehi
Oct 22, 2020·European Journal of Nutrition·Juliana Arruda de Souza MonneratRenata Frauches Medeiros
May 18, 2021·Frontiers in Veterinary Science·Maria Giovanna CilibertiMariangela Caroprese
Oct 26, 2021·Zygote : the Biology of Gametes and Early Embryos·D C C BritoJ R Figueiredo

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