Dietary restraint and menstrual cycle phase modulated L-phenylalanine-induced satiety

Physiology & Behavior
Rachael J Pohle-KrauzaChristine L Pelkman

Abstract

l-phenylalanine (Phe) has been shown to elicit release of the gut hormone cholecystokinin (CCK) and reduce energy intake. Furthermore, studies in some animal models demonstrate potentiation of CCK-induced satiety by estradiol (E(2)). As E(2) is elevated in the follicular phase, we expected greater satiety effects than in the luteal phase when the effects may be antagonized by concomitant elevations in progesterone (P). Women with low dietary restraint were tested over two cycles and received encapsulated Phe or dextrose (control) during both phases within each cycle. Data from 20 women and 32 menstrual cycles were analyzed. Daily energy intake was suppressed by 9% for Phe compared to control and 8% in the follicular versus luteal phase of the menstrual cycle. Significant three-way interactions showed that the effects of condition and phase differed as a function of status on the rigid dietary restraint subscale. Phe suppressed daily energy intake by 15% relative to control in the follicular phase for women in the lower 50th percentile of rigid restraint, whereas for women in the higher 50th percentile group, Phe reduced energy intake by 15% in the luteal phase. The results replicate previous findings showing effects of cycle ph...Continue Reading

References

May 1, 1977·The American Journal of Clinical Nutrition·J Gibbs, G P Smith
Jan 1, 1975·Journal of Comparative and Physiological Psychology·G N Wade
Dec 1, 1975·Journal of Personality·C P Herman, D Mack
Apr 1, 1992·Fertility and Sterility·U SchweigerK M Pirke
Jan 1, 1991·Progress in Neuro-psychopharmacology & Biological Psychiatry·R Mathur, S K Manchanda
Mar 1, 1990·Physiology & Behavior·J Ogden, J Wardle
Feb 1, 1989·The American Journal of Clinical Nutrition·E J GongD H Calloway
May 1, 1987·Ergonomics·A Hedge
Jan 1, 1987·Physiology & Behavior·M Ryan-HarshmanG H Anderson
Apr 1, 1987·Appetite·G A KingJ Polivy
Jan 1, 1987·Psychosomatic Medicine·B Olasov, J Jackson
Jan 1, 1985·Journal of Psychosomatic Research·A J Stunkard, S Messick
Jun 1, 1973·Proceedings of the Society for Experimental Biology and Medicine·S J KonturekA Dembinski
Apr 1, 1972·The American Journal of Physiology·J H Meyer, M I Grossman
Aug 1, 1983·Physiology & Behavior·S P Dalvit-McPhillips
Nov 19, 1982·European Journal of Pharmacology·M S Anika
Nov 1, 1982·Psychological Medicine·D M GarnerP E Garfinkel
Sep 1, 1981·The American Journal of Clinical Nutrition·S P Dalvit
Sep 1, 1995·Journal of the American Dietetic Association·D J Shide, B J Rolls
Oct 1, 1994·The American Journal of Clinical Nutrition·B J RollsS A Stoner
Jan 1, 1995·The American Journal of Clinical Nutrition·S I BarrJ C Prior
May 1, 1994·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·I I Bolaji
Sep 30, 1994·Annals of the New York Academy of Sciences·D De ZieglerP Bouchard
Jan 1, 1994·Peptides·S C Dulawa, D A Vanderweele
Jun 1, 1993·Physiology & Behavior·P C ButeraN J Cataldo
Jan 1, 1993·The American Journal of Clinical Nutrition·A K Fong, M J Kretsch
Oct 1, 1996·The American Journal of Clinical Nutrition·C L RockM A Demitrack
Apr 7, 1999·Annals of Epidemiology·R E PattersonT Agurs-Collins
Jun 1, 1999·The International Journal of Eating Disorders·J WestenhoeferV Pudel
Jan 12, 2001·Obstetrics and Gynecology·E GuermandiP Crosignani
Mar 10, 2001·Eating and Weight Disorders : EWD·C F SmithD H Ryan

❮ Previous
Next ❯

Citations

Jun 23, 2009·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Catherine Sabiston
Sep 17, 2016·Annales d'endocrinologie·Ines KammounClaude Ben Slama
Aug 2, 2013·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Lori Asarian, Nori Geary
Mar 24, 2017·Human Reproduction Update·Brigitte LeenersLori Asarian
Jul 25, 2009·Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición·Sonia A TucciJason C Halford

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antipsychotic-Induced Weight Gain

Antipsychotic-induced weight gain (aiwg) is a common adverse effect of this treatment, particularly with second-generation antipsychotics, and it is a major health problem around the world. Here are the latest discoveries pertaining to AIWG.