PMID: 9176824Jun 1, 1997Paper

Dietary sodium reduction: is there cause for concern?

Journal of the American College of Nutrition
S Kumanyika, J A Cutler

Abstract

Current dietary guidance includes a recommendation for moderate reduction of sodium (Na) intake of US adults to less than 2400 mg (approximately 100 mmol) per day. The safety of this recommendation tends to be taken for granted, but questions are raised periodically about possible adverse effects. We evaluated the evidence available to address these concerns. Relevant sources were identified through review of policy documents and a systematic MEDLINE search of articles published between 1984 and mid-October 1995. Reviews and commentaries were selected to encompass the spectrum of arguments for or against possible adverse effects. All identified randomized, human intervention trials of Na reduction with at least 6 months' follow up and urinary Na excretion data were included; selected additional evidence was evaluated as needed to address specific issues. Reports of trials were abstracted to describe relevant design features, study populations, level of Na reduction, and comments or data relevant to adverse effects. We found that some concerns were based on short-term, Na-depletion studies and were, therefore, not relevant to moderate Na reduction in the population-at-large. Other concerns were largely speculative and, from our ...Continue Reading

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Citations

Feb 14, 2003·The New England Journal of Medicine·Phyllis August
Nov 9, 2010·Journal of Developmental and Behavioral Pediatrics : JDBP·Natalie A WilliamsMarion Hare
Jun 8, 2001·Evaluation Review·D A Freedman, D B Petitti
Jan 7, 2004·Hypertension·David W HarshaLawrence J Appel
Nov 3, 2005·Nature Clinical Practice. Cardiovascular Medicine·Edward D Frohlich, Jasmina Varagic
May 9, 2000·The American Journal of Clinical Nutrition·N M Kaplan
Jan 25, 2002·Current Controlled Trials in Cardiovascular Medicine·William M VollmerLaura P Svetkey
Feb 13, 2001·The Journal of Nutrition·C M LoriaN D Ernst

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