Dietary supplementation with an amino acid blend enhances intestinal function in piglets

Amino Acids
Dan YiGuoyao Wu

Abstract

The traditionally classified nutritionally non-essential amino acids are now known to be insufficiently synthesized for maximal growth and optimal health in piglets. This study determined the effects of dietary supplementation with an amino acid blend (AAB; glutamate:glutamine:glycine:arginine:N-acetylcysteine = 5:2:2:1:0.5) on piglet growth performance and intestinal functions. Sixteen piglets (24-day-old) were randomly assigned to a corn and soybean meal-based diet supplemented with 0.99% alanine (isonitrogenous control) or 1% AAB. On day 20 of the trial, blood and intestinal tissue samples were obtained from piglets. Compared with the control, AAB supplementation reduced (P < 0.05) diarrhoea incidence; plasma alanine aminotransferase and diamine oxidase activities; intestinal concentrations of hydrogen peroxide, malondialdehyde, and heat shock protein-70, and intestinal mRNA levels for interleukin-1β, interferon-γ, and chemokine (C-X-C motif) ligand-9; and the numbers of Enterobacterium family, Enterococcus genus and Clostridium coccoides in the colon digesta. Furthermore, AAB supplementation enhanced (P < 0.05): the plasma concentrations of serine, aspartate, glutamate, cysteine, tyrosine, phenylalanine, tryptophan, lysine,...Continue Reading

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Citations

Jun 28, 2019·Frontiers in Veterinary Science·Zhongyue Yang, Shengfa F Liao
May 10, 2020·Alimentary Pharmacology & Therapeutics·Timur LiwinskiChristoph Schramm
Jun 10, 2020·Journal of Animal Science and Biotechnology·Chaoyue WenYulong Yin
Apr 4, 2021·Journal of Animal Physiology and Animal Nutrition·Hao LvAnshan Shan
Jul 16, 2021·Frontiers in Veterinary Science·Yewande O FasinaSierra Muzquiz
Sep 4, 2021·Amino Acids·Monika RiedererMoenie van der Kleyn

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Methods Mentioned

BETA
scraping
electrophoresis
PCR

Software Mentioned

Leica Application Suite
SPSS13

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