Dietary supplementation with phosphorylated mannans improves growth response and modulates immune function of weanling pigs

Journal of Animal Science
M E DavisT J Wistuba

Abstract

Phosphorylated mannans derived from the yeast cell wall of Saccharomyces cerevisiae may beneficially modulate immune function in the weanling pig, possibly providing an alternative to the use of dietary growth-promoting antibiotics. Therefore, in this study, 32 pigs averaging 19 d of age and 5.7 +/- 0.2 kg initial BW were randomly assigned to 16 pens in an environmentally controlled nursery to determine the effects of dietary supplementation with phosphorylated mannans on growth and immune function. Average daily gain and G:F ratio increased (P < 0.05) when pigs were fed diets supplemented with mannans from d 0 to 14 after weaning and in the overall experiment. Percentage of neutrophils was lower (P < 0.08) and percentage of lymphocytes was higher (P < 0.05) in blood from pigs fed mannans than when pigs were fed the basal diet. Lamina propria macrophages isolated from pigs fed diets containing mannans phagocytosed a greater (P < 0.05) number of sheep red blood cells (2.63 +/- 0.11) than did lamina propria macrophages isolated from pigs fed the basal diet (2.31 +/- 0.11). On d 19 after weaning, pigs fed diets supplemented with mannans tended to have a greater (P < 0.10) percentage of CD14+ lamina propria leukocytes than did pigs...Continue Reading

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Citations

Jul 5, 2007·Journal of Animal Science·C M C van der Peet-SchweringI Yoon
May 13, 2014·Journal of the Science of Food and Agriculture·Kieran JordanMindaugas Malakauskas
Nov 3, 2016·Journal of Animal Physiology and Animal Nutrition·W LiermannS Dänicke
Mar 24, 2012·Animal : an International Journal of Animal Bioscience·M H KimJ K Ha
May 1, 2007·The Proceedings of the Nutrition Society·Jean-Paul LallèsChris R Stokes
Aug 15, 2008·Journal of Animal Physiology and Animal Nutrition·I NochtaL Babinszky
Dec 1, 2009·Animal : an International Journal of Animal Bioscience·M GalloisI P Oswald
Feb 13, 2013·Journal of Animal Science·B BassC Maxwell
Sep 16, 2008·Journal of Animal Science·C Farmer, H Quesnel
Jan 1, 2012·Animals : an Open Access Journal From MDPI·Veronika Halas, Imre Nochta
Jan 9, 2021·Journal of Animal Science and Biotechnology·Bocheng XuYizhen Wang
Feb 6, 2021·Animals : an Open Access Journal From MDPI·Nicole C Burdick SanchezJeffery A Carroll
Dec 17, 2020·Animals : an Open Access Journal From MDPI·Waewaree BoontiamSuchat Wattanachai
Jun 21, 2011·Chemical Reviews·Päivi Mäki-ArvelaDmitry Yu Murzin
Dec 8, 2021·Animal Science Journal = Nihon Chikusan Gakkaihō·Siriporn NamtedChaiyapoom Bunchasak

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