Dietary therapy in polycystic ovary syndrome

Seminars in Reproductive Medicine
Lisa MoranRobert J Norman

Abstract

Polycystic ovary syndrome (PCOS) is a common condition in women with reproductive age associated with reproductive and metabolic dysfunction. Treatment has traditionally focused on fertility and hormonal therapy. However, obesity, central obesity, and insulin resistance (IR) are strongly implicated in its etiology, and improving these factors has become a treatment target in PCOS. Lifestyle modification programs with an emphasis on behavioral management and dietary and exercise interventions have been successful in reducing the risk of diabetes and the metabolic syndrome in the general population and improving reproductive and metabolic features in PCOS, although as yet there is limited evidence for specific dietary and exercise approaches and guidelines for use in PCOS and requires further investigation. The use of antiobesity pharmacologic agents and bariatric surgery has been recently studied in PCOS and may offer additional treatment options for the future. Future research should focus on the optimal dietary strategies and exercise regimens for PCOS treatment and the relative efficacy and appropriate use of lifestyle management versus antiobesity pharmacologic agents and surgery.

Citations

Jun 29, 2011·Seminars in Reproductive Medicine·Vasantha Padmanabhan, Almudena Veiga-Lopez
Aug 10, 2012·Behavioral Medicine·Samantha L KozicaLisa J Moran
May 27, 2009·Current Opinion in Obstetrics & Gynecology·Elizabeth H RuderMarlene B Goldman
Jul 29, 2008·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Aldo GalluzzoCarla Giordano
Jun 12, 2010·Diabetic Medicine : a Journal of the British Diabetic Association·J TomlinsonJ Pinkney
Mar 1, 2012·American Journal of Obstetrics and Gynecology·Jennifer P Beller, Christopher R McCartney
Sep 17, 2016·International Journal of Endocrinology·Lali PkhaladzeNana Kvashilava
Nov 4, 2016·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Mette Mandrup KjærLisbeth Nilas
Sep 8, 2016·European Journal of Endocrinology·Dorte Glintborg, Marianne Andersen
Jul 8, 2011·The Cochrane Database of Systematic Reviews·Lisa J MoranHelena J Teede
Sep 19, 2008·Journal of Cardiovascular Medicine·Francesco GiallauriaCarlo Vigorito
Nov 7, 2019·International Journal of Molecular Sciences·Michele d'AngeloElisabetta Benedetti
Feb 2, 2021·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Xin ZhengChangqin Liu

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