PMID: 9665114Jul 17, 1998Paper

Dietary treatment of severe malnutrition in adults

The American Journal of Clinical Nutrition
S CollinsB Golden

Abstract

The aim of this study was to compare the effects of two diets, differing primarily in protein content, on the nutritional rehabilitation of severely malnourished adults. The study took place in the Concern Worldwide Adult Therapeutic Feeding Centre in Baidoa, the town at the epicenter of the 1992 famine in Somalia. The response to treatment in 573 patients admitted to the center between November 1992 and March 1993 was studied. Mortality, appetite, rates of edema loss, and weight gain in 2 groups of patients receiving either a higher-protein (16.4% of energy from protein) or lower-protein (8.5% of energy from protein) diet were compared. Among edematous patients, the use of the lower-protein diet during the initial phase of treatment was associated with a threefold decrease in mortality (P < 0.05) and accelerated resolution of edema (P < 0.05). Among marasmic patients, no differences in mortality or rate of weight gain were observed. The large reduction in mortality associated with the use of the lower-protein diet in edematous patients appeared to be due to the lower amount of dietary protein. However, differences in the 2 diets other than or in addition to the protein content may have contributed. Notwithstanding, the data ob...Continue Reading

Citations

Feb 24, 2001·Nature·G L Blackburn
Jan 30, 2015·BMC Medicine·UNKNOWN NUSTART (Nutritional Support for Africans Starting Antiretroviral Therapy) Study TeamPaul Kelly
Apr 5, 2000·Transactions of the Royal Society of Tropical Medicine and Hygiene·B E GoldenM H Golden
Jan 21, 2000·Current Opinion in Clinical Nutrition and Metabolic Care·V Scherbaum, P Fürst
Aug 29, 2002·The American Journal of Clinical Nutrition·Alan A Jackson
Mar 9, 2007·The Proceedings of the Nutrition Society·Jeremy Powell-Tuck
May 16, 2015·Paediatrics and International Child Health·Alan A Jackson
Mar 26, 2014·Journal of the European Academy of Dermatology and Venereology : JEADV·S HeilskovM S Deleuran
Sep 16, 2006·Journal of Paediatrics and Child Health·David R Brewster
Jul 20, 2007·The Proceedings of the Nutrition Society·Mike Stroud
Oct 26, 2010·Indian Pediatrics·Michael H Golden
Jul 20, 2012·The American Journal of Clinical Nutrition·L John Hoffer, Bruce R Bistrian
Jul 5, 2002·The Journal of Nutrition·Michael H N Golden
Nov 16, 2004·Lancet·Peter SalamaRonald Waldman

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