Diethyl 2-{[2-(trifluoro-meth-yl)anil-ino]methyl-idene}propane-dioate.

Acta Crystallographica. Section E, Structure Reports Online
B GarudachariRichard Betz

Abstract

The title compound, C(15)H(16)F(3)NO(4), is an N-substituted derivative of ortho-trifluoro-methyl-aniline featuring a twofold Michael system. The least-squares planes defined by the atoms of the phenyl ring and the atoms of the Michael system enclose an angle of 15.52 (5)°. Apart from classical intra-molecular N-H⋯O and N-H⋯F hydrogen bonds, inter-molecular C-H⋯O contacts are observed, the latter connecting the mol-ecules into chains along [110]. The shortest inter-centroid distance between two aromatic systems is 3.6875 (9) Å.

References

Apr 1, 1990·Acta Crystallographica. Section B, Structural Science·M C EtterJ Bernstein
Nov 24, 2004·Bioorganic & Medicinal Chemistry·Yeh-Long ChenCherng-Chyi Tzeng
Dec 25, 2007·Acta Crystallographica. Section A, Foundations of Crystallography·George M Sheldrick
Jan 28, 2009·Acta Crystallographica. Section D, Biological Crystallography·Anthony L Spek
Jun 23, 2009·European Journal of Medicinal Chemistry·Ramya V ShingalapurRangappa S Keri
Aug 4, 2009·European Journal of Medicinal Chemistry·Sumesh EswaranN Suchetha Shetty
May 15, 2010·European Journal of Medicinal Chemistry·Kirandeep KaurRahul Jain
Jun 12, 2010·European Journal of Medicinal Chemistry·Sumesh EswaranK D Thomas

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