PMID: 9420623Jan 8, 1998Paper

Difference in binding of killed and live Streptococcus pneumoniae serotypes by C-reactive protein

Scandinavian Journal of Immunology
A J de BeaufortR van Furth

Abstract

The binding and opsonic properties of C-reactive protein (CRP) for various species of bacteria were investigated. CRP bound more avidly to killed than to live Streptococcus pneumoniae, the binding varying among various serotypes; CRP hardly bound to a number of other bacterial species studied. CRP enhanced complement-dependent phagocytosis of live S. pneumoniae by granulocytes but did not enhance the phagocytosis of live Staphylococcus aureus or group B streptococci. We suppose that CRP may serve as an opsonin for killed bacteria and bacterial debris but is probably not an important opsonin for live bacteria other than S. pneumoniae.

Citations

Aug 14, 2003·Molecular Immunology·Hanna JarvaSeppo Meri
Dec 8, 2007·American Journal of Physiology. Gastrointestinal and Liver Physiology·Kjetil ElvevoldInigo Martinez
Jan 15, 2011·Archives of Microbiology·Catherine EngPierre Leblond
Jan 5, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Madathilparambil V SureshAlok Agrawal
Mar 14, 2019·Frontiers in Immunology·Donald N Ngwa, Alok Agrawal
Oct 12, 1999·The American Journal of Physiology·W I MariencheckJ R Wright

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