Difference in epicardial adipose tissue distribution between paroxysmal atrial fibrillation and coronary artery disease

Heart and Vessels
Hideyuki HasebeMasaki Ieda

Abstract

An increase in epicardial adipose tissue (EAT) volume is associated with the development of atrial fibrillation (AF) and coronary artery disease (CAD), but little is known about differences in its distribution. We included 50 patients with paroxysmal AF (PAF), 50 patients with CAD, and 50 control patients. Using multidetector computed tomography, EAT volumes surrounding the whole heart (total EAT), the atrium (atrial-EAT), and the ventricle (ventricular-EAT) were measured. EAT atrial/ventricular (A/V) ratio was calculated by dividing atrial- by ventricular-EAT volume. The total EAT volume indexes in the PAF and CAD groups were significantly larger than those in the control group. The atrial-EAT volume index in the PAF group was significantly larger than that in the CAD and control groups, whereas the ventricular-EAT volume index in the CAD group was significantly larger than that in the PAF and control groups. Thus, EAT A/V ratio was smaller in the CAD and control group than that in the PAF group (0.28 ± 0.12 vs. 0.38 ± 0.13 vs. 0.54 ± 0.33, P < .001). Univariate and multivariate linear regression analysis showed EAT A/V ratio to be independently associated with cardiovascular disease type (PAF vs. CAD; P < .001, β = .463). Atr...Continue Reading

References

Oct 29, 2003·Circulation·Tomasz MazurekYi Shi
Mar 23, 2007·AJR. American Journal of Roentgenology·Abdel-Rauf ZeinaElisha Barmeir
Jul 22, 2009·Circulation·Yukio IshikawaToshiharu Ishii
Jun 19, 2010·Circulation. Arrhythmia and Electrophysiology·George ThanassoulisEmelia J Benjamin
Apr 23, 2011·Journal of the American College of Cardiology·Christopher X WongPrashanthan Sanders
Jul 9, 2011·Journal of the American College of Cardiology·Yoichiro HirataMasataka Sata
Feb 2, 2012·European Heart Journal Cardiovascular Imaging·Tsuyoshi ItoTakahiko Suzuki
Aug 17, 2012·American Journal of Physiology. Endocrinology and Metabolism·Sam CherianEugenia Carvalho
Sep 14, 2012·Circulation Journal : Official Journal of the Japanese Circulation Society·Koki NakanishiMinoru Yoshiyama
Apr 16, 2013·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Martin GreifAlexander Becker
Mar 22, 2014·Cardiovascular Research·Stéphane N Hatem, Prashanthan Sanders
Feb 12, 2017·Circulation. Arrhythmia and Electrophysiology·Alexander R van RosendaelJeroen J Bax
Oct 10, 2018·International Journal of Cardiology·Anna Maria AnsaldoFederico Carbone

❮ Previous
Next ❯

Citations

May 19, 2021·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Marinela Couselo-SeijasSonia Eiras

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Cardiovascular Inflammation

Inflammation plays a significant role in the development of cardiovascular diseases, an understanding of these endogenous processes is critical for evaluating the risks and potential treatment strategies. Discover the latest research on cardiovascular inflammation here.