PMID: 8600363Mar 9, 1996Paper

Difference in types of radiation-induced structural chromosome aberrations and their incidences between Chinese and Syrian hamster spermatozoa

Mutation Research
H TatenoK Mikamo

Abstract

The effects of ionizing radiations on sperm chromosomes were studied in the Chinese hamster (Crisetulus griseus) and the Syrian (golden) hamster (Mesocrisetus auratus). Testes of mature male Chinese hamsters (CH) were irradiated with X-rays (0.91, 1.82 and 3.63 Gy) and gamma-rays (1.10, 2.15, 2.95 and 4.01 Gy) at a single acute dosage, whereas the irradiation was done with lower doses of X-rays (0.45, 0.91 and 1.82 Gy) and gamma-rays (0.49, 0.99 and 1.98 Gy) in mature male Syrian hamsters (SH), taking the higher radiosensitivity of this species into consideration. They were mated with normal females within 6 days of exposure. Sperm-derived chromosomes were analyzed in 1125 and 1966 fertilized ova of the CH and the SH, respectively. In both species, there was no great difference in the induction of structural chromosome aberrations between X-irradiated and gamma-irradiated spermatozoa. Chromosome-type aberrations were predominantly induced. The incidence of breakage-type aberrations increased linearly, and that of exchange-type aberrations linear-quadratically with increase of dosage. A species-specific difference in chromosomal radiosensitivity of spermatozoa was clear. In spite of the same radiation dosage, the incidence of ch...Continue Reading

References

Jan 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·W M GenerosoS W Huff
Sep 1, 1976·Mutation Research·A LeonardG h Deknudt
Jan 1, 1988·Environmental and Molecular Mutagenesis·B F BrandriffA V Carrano
Mar 1, 1980·Mutation Research·P P van Buul, A T Natarajan

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Citations

May 1, 1997·Molecular Reproduction and Development·H Tateno, Y Kamiguchi
Jul 11, 2002·Mutation Research·Yujiroh Kamiguchi, Hiroyuki Tateno
Oct 2, 2008·Reproduction : the Official Journal of the Society for the Study of Fertility·Hossein Mozdarani, Elmina Nazari
Dec 7, 2006·International Journal of Radiation Biology·Hossein Mozdarani, Mahdieh Salimi

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