Differences between juvenile-onset ankylosing spondylitis and adult-onset ankylosing spondylitis

Journal of the Chinese Medical Association : JCMA
Yi-Chun LinHsiao-Yi Lin

Abstract

Ankylosing spondylitis (AS) is a chronic inflammatory disease, which involves the spine, peripheral joints and entheses. Juvenile-onset ankylosing spondylitis (JAS) affects children under the age of 16 years. JAS has been noted to present as clinical courses different from those of adult-onset ankylosing spondylitis (AAS). Therefore, the purpose of the present study was to compare the possible risk factors, clinical manifestations, laboratory markers, radiological changes, and functional outcome between these 2 patient groups. AS patients were enrolled from the rheumatologic clinic of a tertiary medical center from January 1 to June 30 in 2006. The demographic data, clinical symptoms/signs, Bath AS indices, HLA-B27, inflammatory markers, radiological findings, and treatment history were acquired with questionnaires, clinical evaluation, and chart review. The differences between JAS and AAS patients were evaluated and analyzed. A total of 169 patients (142 males, 27 females) were included, comprising 47 JAS and 122 AAS patients. The ages of onset were 12.8 +/- 2.7 years and 25.0 +/- 7.4 years for JAS and AAS, respectively. They had similar gender distribution, years of delay to diagnosis and disease duration. A substantial propo...Continue Reading

References

Aug 1, 1990·Research in Nursing & Health·M E Wewers, N K Lowe
Oct 1, 1989·Annals of the Rheumatic Diseases·G S Panayi
Dec 1, 1985·Annals of the Rheumatic Diseases·G MassonM Alcalay
Jan 1, 1983·Scandinavian Journal of Rheumatology·O García-MorteoE Garay
Jan 1, 1996·British Journal of Rheumatology·S D JonesA Calin
Aug 1, 1997·Rheumatic Diseases Clinics of North America·R Burgos-VargasJ Vázquez-Mellado
Oct 31, 2000·Clinical Rheumatology·J B JunS Y Kim
Sep 14, 2001·Current Opinion in Rheumatology·K L Hyrich, R D Inman
Jun 24, 2003·Current Opinion in Rheumatology·Marjatta Leirisalo-RepoLeena Mattila
Dec 5, 2003·Rheumatology International·Amita AggarwalRamnath Misra
Mar 31, 2004·Annals of the Rheumatic Diseases·M C W CreemersP L C M van Riel
May 25, 2004·Seminars in Nephrology·Jonathan BarrattAlice C Smith
Jun 1, 2005·The American Journal of Medicine·John D Reveille, Frank C Arnett
Oct 3, 2006·Seminars in Arthritis and Rheumatism·Mark MansourM Eric Gershwin

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Citations

Apr 3, 2012·International Journal of Rheumatic Diseases·Hai-jun MaQing-yu Xu
Dec 24, 2009·Journal of the Chinese Medical Association : JCMA·Chang-Youh Tsai
Dec 3, 2014·Revista brasileira de reumatologia·Angela P DuartePercival D Sampaio Barros
Apr 11, 2012·Nature Reviews. Rheumatology·Shirley M L Tse, Ronald M Laxer
May 28, 2017·Clinical Rheumatology·Qiaoxia QianJiucun Wang
Jan 17, 2020·Pediatric Rheumatology Online Journal·Shruti BhattacharyaAmita Aggarwal
Jan 8, 2021·Pediatric Rheumatology Online Journal·Nassem GhantousGil Amarilyo
Jun 18, 2021·Frontiers in Medicine·Corinne FisherLucy R Wedderburn
Nov 24, 2021·Expert Review of Clinical Immunology·Lassoued Ferjani HaneneWafa Hamdi
Jun 18, 2019·Joint, Bone, Spine : Revue Du Rhumatisme·Jacqueline L HayworthJanet E Pope

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