Differences between male and female patients with regard to baseline demographics and clinical outcomes in the Asymptomatic Cardiac Ischemia Pilot (ACIP) Trial

Clinical Cardiology
W H FrishmanS Forman

Abstract

Coronary artery disease (CAD) is a common problem in men and women; however, men and women with similar clinical presentations of myocardial ischemia may receive different revascularization treatments. Using the data base of the Asymptomatic Cardiac Ischemia Pilot (ACIP) trial, this study was undertaken to compare by gender the baseline demographic data and the clinical outcome results in patients randomized to various treatments in the ACIP study. This randomized trial compared three treatment regimens [pharmacologic management of angina, pharmacologic management of angina and ambulatory electrocardiographic (ECG) evidence of ischemia, and revascularization--that is, angioplasty and coronary artery bypass surgery], in patients with known CAD, positive stress ECG tests, and ECG evidence of ischemia during 48 h ambulatory monitoring. In all, 558 patients were randomized, 79 of whom were women (mean age: men 61.6 years, women 60.6 years) Ambulatory ECG evidence of ischemia, clinical events, that is, death, myocardial infarction, hospital admission for coronary events, and exercise performance were monitored. Although of the same age as men at baseline, women had a higher prevalence of hypertension and diabetes. Women had less sev...Continue Reading

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Citations

Oct 11, 2012·Current Problems in Cardiology·Eveline Oestreicher Stock, Rita Redberg
Sep 11, 2007·Journal of the American College of Cardiology·Timothy D HenryRobert L Engler
Sep 11, 2008·Diabetes Care·Carlo B GiordaUNKNOWN Diabetes and Informatics Study Group
Mar 17, 2004·Coronary Artery Disease·Venkatesan SangareddiS Elangovan

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