Differences between the clinical and histopathological tumor stages in breast cancer diagnosed using vacuum-assisted breast biopsy

Oncology Letters
Hai-Lin ParkSongmi Noh

Abstract

The present study aimed to determine the difference between the clinical tumor stage (T stage) based on pre-operative ultrasound and the histopathological T stage subsequent to surgery in vacuum-assisted breast biopsy (VABB)-diagnosed breast cancer. Tumor sizes measured ultrasonography (USG) and histologically were retrospectively calculated and analyzed using paired t-tests in 209 patients diagnosed with breast cancer using VABB. The patients were classified into two groups, consisting of breast imaging reporting and data system (BI-RADS) category 4a or below, who underwent complete resection by VABB, and BI-RADS category 4b or above, who underwent incisional biopsy by VABB. The histopathological tumor size was found to be smaller compared with the USG-determined size in 92.3% of pT1a, 75.5% of pT1b, 44.2% of pT1c, 47.7% of pT2 and 0% of pT3 cases. Furthermore, the histopathological tumor size was smaller compared with the USG-determined size in 62.8% of cases classified as BI-RADS category 3-4a and in 53.7% of cases classified as BI-RADS category 4b-5. The smaller the primary tumor at the time of diagnosis by VABB, the higher the likelihood of pathological underestimation on post-operative histopathological assessment compare...Continue Reading

References

Jan 1, 1992·Breast Cancer Research and Treatment·G M Clark
Jan 1, 1992·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J A van DongenJ Winter
Jan 1, 1988·Ultrasound in Medicine & Biology·S NishimuraS Kashihara
Mar 1, 1988·The British Journal of Surgery·D J WarwickI Taylor
Nov 1, 1983·Journal of Clinical Ultrasound : JCU·R W LambieM Kopperman
Jun 1, 1984·The British Journal of Surgery·B O Maehle, R Skjaerven
Feb 1, 1995·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·H MedenW Kuhn
Jul 4, 1998·International Journal of Radiation Oncology, Biology, Physics·D CowenD Maraninchi
Mar 27, 2001·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·U VeronesiG Viale
Nov 27, 2001·American Journal of Surgery·T J HiekenJ M Velasco

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Methods Mentioned

BETA
biopsy
surgical
X-ray

Software Mentioned

SPSS

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