Differences in Anticipatory Behaviour between Rats (Rattus norvegicus) Housed in Standard versus Semi-Naturalistic Laboratory Environments

PloS One
I Joanna Makowska, Daniel M Weary

Abstract

Laboratory rats are usually kept in relatively small cages, but research has shown that they prefer larger and more complex environments. The physiological, neurological and health effects of standard laboratory housing are well established, but fewer studies have addressed the sustained emotional impact of a standard cage environment. One method of assessing affective states in animals is to look at the animals' anticipatory behaviour between the presentation of a cue signalling the arrival of a reward and the arrival of that reward. The primary aim of this study was to use anticipatory behaviour to assess the affective state experienced by female rats a) reared and housed long-term in a standard laboratory cage versus a semi-naturalistic environment, and b) before and after treatment with an antidepressant or an anxiolytic. A secondary aim was to add to the literature on anticipatory behaviour by describing and comparing the frequency and duration of individual elements of anticipatory behaviour displayed by rats reared in these two systems. In all experiments, total behavioural frequency was higher in standard-housed rats compared to rats from the semi-naturalistic condition, suggesting that standard-housed rats were more se...Continue Reading

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Citations

Jul 19, 2016·Royal Society Open Science·I Joanna Makowska, Daniel M Weary
Oct 30, 2019·The European Journal of Neuroscience·Samantha R EckDebra A Bangasser
Apr 21, 2020·ILAR Journal·I Joanna Makowska, Daniel M Weary
Dec 14, 2019·Scientific Reports·Lucía AméndolaDaniel M Weary
Sep 22, 2019·Animals : an Open Access Journal From MDPI·Jason V Watters, Bethany L Krebs
Dec 15, 2019·Animals : an Open Access Journal From MDPI·Hibba Mazhary, Penny Hawkins

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