Differences in clinical manifestation of Streptococcus pneumoniae infection are not correlated with in vitro production and release of the virulence factors pneumolysin and lipoteichoic and teichoic acids

Journal of Clinical Microbiology
Annette SpreerRoland Nau

Abstract

Production and release of the pneumococcal virulence factors pneumolysin and lipoteichoic and teichoic acid in 75 clinical isolates were investigated. No difference was found between strains causing systemic infection or localized respiratory infection and isolates from asymptomatic carriers. This suggests that the presence of pneumolysin and lipoteichoic and teichoic acid is a necessary but not a sufficient condition for pneumococcal infection and development of invasive disease.

References

Feb 1, 1987·Journal of Clinical Microbiology·K Kanclerski, R Möllby
Mar 1, 1985·Reviews of Infectious Diseases·L A BurmanB Trollfors
Jan 1, 1995·The Journal of Clinical Investigation·J B RubinsE N Janoff
Feb 1, 1994·The Journal of Infectious Diseases·J B DaleM S Bronze
Sep 17, 1998·The Journal of Antimicrobial Chemotherapy·B P GoldsteinR Novick
May 31, 2001·Microbiology and Molecular Biology Reviews : MMBR·M J Jedrzejas
Aug 7, 2001·Journal of Immunoassay & Immunochemistry·M D Cima-CabalJ R de los Toyos
Jan 10, 2002·The Journal of Clinical Investigation·Johann S BraunJoerg R Weber
Apr 12, 2002·The Lancet Infectious Diseases·Isaac Ginsburg
May 17, 2002·Current Opinion in Infectious Diseases·Riana CockeranCharles Feldman

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Citations

May 25, 2007·Critical Care Medicine·Martin WitzenrathHartwig Schütte
May 30, 2006·The Pediatric Infectious Disease Journal·Edith L G M TonnaerJo H A J Curfs
Aug 31, 2007·Journal of Clinical Microbiology·María del Mar García-SuárezFrancisco J Méndez
Jul 12, 2014·PloS One·Anne L WyllieKrzysztof Trzciński

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