Differences in cochlear nerve cross-sectional area between normal hearing and postlingually deafened patients on MRI

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
Björn Herman, Simon Angeli

Abstract

To demonstrate that parasagittal constructive interference in steady state (CISS) magnetic resonance imaging (MRI) can be used to accurately measure cochlear nerve cross-sectional area and thereby evaluate for statistically significant differences in the cochlear nerve cross-sectional areas of postlingually deafened and normal-hearing adults. Cross-sectional study. Tertiary care medical center. Parasagittal CISS MRIs of postlingually profoundly deafened cochlear implant candidates and normal-hearing patients at a tertiary care academic medical center between 2006 and 2009 were retrospectively identified. Two independent and blinded investigators measured the cochlear nerve height and width and calculated the cross-sectional area [π(H/2)(W/2)] at the fundus of the internal auditory canals. Measurements of both investigators were analyzed for reliability and agreement with an Altman plot, and deafened patient measurements were compared with results of the normal-hearing patients via Wilcoxon rank sum tests. The cochlear nerve cross-sectional area of postlingually deafened patients (mean ± SD = 0.61 ± 0.16 mm(2)) was less than normal-hearing patients (0.94 ± 0.28 mm(2)). The difference was statistically significant (P = .002). The...Continue Reading

References

Dec 11, 1992·The Annals of Otology, Rhinology, and Laryngology·J B Nadol, W Z Xu
Apr 14, 2004·Acta Oto-laryngologica. Supplementum·Takeshi MoritaJuichi Ito
Aug 4, 2009·The Laryngoscope·Eric M JaryszakPatrick J Antonelli

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Citations

Nov 1, 2013·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Rei NakamichiShinji Naganawa
May 12, 2015·International Journal of Pediatric Otorhinolaryngology·Jing LouGuang-Bin Wang
Oct 8, 2013·Diagnostic and Interventional Imaging·F BenoudibaJ-L Sarrazin
Apr 7, 2016·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Catherine S BirmanElizabeth J Elliott
Jul 1, 2017·Current Opinion in Otolaryngology & Head and Neck Surgery·Justin S Golub
Feb 23, 2020·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·Wolfgang FreundMeinrad Beer

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Methods Mentioned

BETA
cochlear implants
Cochlear Implant
Cochlear Nerve

Software Mentioned

JMP

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