Abstract
Women may be more vulnerable to HIV-related cognitive dysfunction compared with men because of sociodemographic, lifestyle, mental health, and biological factors. However, studies to date have yielded inconsistent findings on the existence, magnitude, and pattern of sex differences. We examined these issues using longitudinal data from 2 large, prospective, multisite, observational studies of US women and men with and without HIV. The Women's Interagency HIV Study (WIHS) and Multicenter AIDS Cohort Study (MACS). HIV-infected (HIV+) and uninfected (HIV-) participants in the Women's Interagency HIV Study and Multicenter AIDS Cohort Study completed tests of psychomotor speed, executive function, and fine motor skills. Groups were matched on HIV status, sex, age, education, and black race. Generalized linear mixed models were used to examine group differences on continuous and categorical demographically corrected T-scores. Results were adjusted for other confounding factors. The sample (n = 1420) included 710 women (429 HIV+) and 710 men (429 HIV+) (67% non-Hispanic black; 53% high school or less). For continuous T-scores, sex by HIV serostatus interactions were observed on the Trail Making Test parts A & B, Grooved Pegboard, and ...Continue Reading
References
Aug 1, 1987·American Journal of Epidemiology·R A KaslowC R Rinaldo
Jun 1, 1993·Perceptual and Motor Skills·R M Ruff, S B Parker
Mar 21, 1998·Epidemiology·S E BarkanJ Feldman
Dec 6, 2000·Brain and Cognition·S L SchmidtY Abreu-Villaça
Aug 21, 2007·Gender Medicine·Ighovwerha OfotokunJane E Hitti
Oct 28, 2008·Psychiatry and Clinical Neurosciences·José M Faílde-GarridoMiguel A Simón-López
May 12, 2009·Neuropsychology Review·Pauline M Maki, Eileen Martin-Thormeyer
Jul 15, 2009·Nature Medicine·Angela MeierMarcus Altfeld
Aug 10, 2010·Journal of Clinical and Experimental Neuropsychology·Eileen MartinPauline Maki
Dec 8, 2010·Neurology·R K HeatonUNKNOWN CHARTER Group
Oct 19, 2011·Journal of Neurovirology·Howard A CrystalRobert C Kaplan
Dec 31, 2011·Public Health·R DetelsS Wolinsky
Feb 6, 2014·Menopause : the Journal of the North American Menopause Society·Leah H RubinPauline M Maki
Apr 29, 2014·International Journal of Epidemiology·James T BeckerOla A Selnes
Jun 27, 2014·The Journal of Infectious Diseases·Marylyn M Addo, Marcus Altfeld
Oct 30, 2014·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Kim M KielyMark Wooden
Nov 2, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Robert K HeatonUNKNOWN CHARTER Group
Dec 30, 2014·Neurology·Pauline M MakiKathryn Anastos
Mar 21, 2015·Journal of Neurovirology·Leah H RubinPauline M Maki
Aug 27, 2015·Journal of Neurovirology·Ashley M Behrman-LayBeau M Ances
Sep 26, 2015·Journal of Neurovirology·Leah H RubinPauline M Maki
Jan 1, 2016·Neurology·Ned SacktorEric Miller
Feb 2, 2016·PloS One·Walter RoyalWilliam A Blattner
Feb 18, 2016·Journal of Clinical and Experimental Neuropsychology·Eileen MartinMatthias Brand
Apr 21, 2016·Journal of Neurovirology·Leah H RubinPauline M Maki
Nov 15, 2016·Journal of Clinical and Experimental Neuropsychology·Michael K KeutmannEileen M Martin
Sep 15, 2017·Neurology·Leah H RubinUNKNOWN Women's Interagency HIV Study
Citations
Mar 21, 2019·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Leah H RubinPauline M Maki
May 21, 2019·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Raha M DastgheybNorman J Haughey
Sep 16, 2019·Current Psychiatry Reports·Leah H RubinPauline M Maki
Jan 17, 2020·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Raeanne C MooreJoel Swendsen
Feb 14, 2019·Journal of Neurovirology·Xiaotong QiaoYingying Ding
Jun 26, 2020·Journal of the International Association of Providers of AIDS Care·Adria QuigleyMarilyn MacKay-Lyons
May 19, 2019·Journal of Neurovirology·Adam R DentonRosemarie M Booze
Nov 17, 2019·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Kelli L SullivanSteven Paul Woods
Apr 24, 2020·Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology·Hua-Jun LiangLinda Chang
Aug 21, 2020·Scientific Reports·Georgette D KanmogneRobert K Heaton
Dec 14, 2018·Frontiers in Behavioral Neuroscience·Kristen A McLaurinRosemarie M Booze
Aug 27, 2019·Frontiers in Behavioral Neuroscience·Landhing M MoranCharles F Mactutus
Aug 28, 2020·The American Journal of Clinical Nutrition·Judy Y TanSheri D Weiser
Jan 5, 2019·Journal of Neurovirology·Kristen A McLaurinCharles F Mactutus
Jan 31, 2019·Scientific Reports·Kristen A McLaurinCharles F Mactutus
Sep 16, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Eric Andrius Coelho DuarteJean Costa Nunes
Sep 19, 2020·Journal of Neuroinflammation·Farina J MahmudAmanda M Brown
Oct 14, 2020·AIDS·Sean B RourkeChristopher Power
Dec 18, 2020·Frontiers in Neurology·Leah H RubinDavid J Moore
Jan 1, 2021·PloS One·Mary F BarbeJennifer Gordon
Dec 29, 2020·Brain, Behavior, and Immunity·Alyssa C VecchioLeah H Rubin
Sep 4, 2020·AIDS and Behavior·Corrina MoucheraudRisa M Hoffman
Dec 22, 2020·Current Treatment Options in Infectious Diseases·Tessa Del CarmenEugenia L Siegler
Feb 23, 2021·Lancet·Adaora A AdimoraMonica Gandhi
Jan 14, 2021·Menopause : the Journal of the North American Menopause Society·Pauline M MakiLeah H Rubin
Jan 16, 2021·The Journal of the Association of Nurses in AIDS Care : JANAC·Drenna WaldropDavid E Vance
May 8, 2021·HIV/AIDS : Research and Palliative Care·Eugenia L SieglerMarshall J Glesby
May 6, 2021·Viruses·Mohammed F SalahuddinJason J Paris
Jun 6, 2021·Scientific Reports·Kristen A McLaurinRosemarie M Booze
Jul 28, 2021·Cognitive, Affective & Behavioral Neuroscience·Benjamin Z RobertsJared W Young
Aug 22, 2021·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Anna J DreyerKevin G F Thomas
May 21, 2019·Progress in Neurobiology·Bianca CottoDianne Langford
Nov 27, 2021·Neuropsychology Review·David E VancePariya L Fazeli
Nov 30, 2021·Current HIV/AIDS Reports·Michael J PelusoFelicia C Chow
Mar 20, 2020·Neurology. Clinical Practice·Sean G AndersonEric H Decloedt
Jan 20, 2022·Journal of Neurovirology·Fan Nils YangXiong Jiang