Differences in Cognitive Function Between Women and Men With HIV

Journal of Acquired Immune Deficiency Syndromes : JAIDS
Pauline M MakiNeuropsychology Working Groups of the Womenʼs Interagency HIV Study and the Multicenter AIDS Cohort Study

Abstract

Women may be more vulnerable to HIV-related cognitive dysfunction compared with men because of sociodemographic, lifestyle, mental health, and biological factors. However, studies to date have yielded inconsistent findings on the existence, magnitude, and pattern of sex differences. We examined these issues using longitudinal data from 2 large, prospective, multisite, observational studies of US women and men with and without HIV. The Women's Interagency HIV Study (WIHS) and Multicenter AIDS Cohort Study (MACS). HIV-infected (HIV+) and uninfected (HIV-) participants in the Women's Interagency HIV Study and Multicenter AIDS Cohort Study completed tests of psychomotor speed, executive function, and fine motor skills. Groups were matched on HIV status, sex, age, education, and black race. Generalized linear mixed models were used to examine group differences on continuous and categorical demographically corrected T-scores. Results were adjusted for other confounding factors. The sample (n = 1420) included 710 women (429 HIV+) and 710 men (429 HIV+) (67% non-Hispanic black; 53% high school or less). For continuous T-scores, sex by HIV serostatus interactions were observed on the Trail Making Test parts A & B, Grooved Pegboard, and ...Continue Reading

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Citations

Mar 21, 2019·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Leah H RubinPauline M Maki
May 21, 2019·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Raha M DastgheybNorman J Haughey
Sep 16, 2019·Current Psychiatry Reports·Leah H RubinPauline M Maki
Jan 17, 2020·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Raeanne C MooreJoel Swendsen
Feb 14, 2019·Journal of Neurovirology·Xiaotong QiaoYingying Ding
Nov 17, 2019·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Kelli L SullivanSteven Paul Woods
Apr 24, 2020·Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology·Hua-Jun LiangLinda Chang
Aug 27, 2019·Frontiers in Behavioral Neuroscience·Landhing M MoranCharles F Mactutus
Aug 28, 2020·The American Journal of Clinical Nutrition·Judy Y TanSheri D Weiser
Jan 5, 2019·Journal of Neurovirology·Kristen A McLaurinCharles F Mactutus
Jan 31, 2019·Scientific Reports·Kristen A McLaurinCharles F Mactutus
Sep 16, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Eric Andrius Coelho DuarteJean Costa Nunes
Dec 18, 2020·Frontiers in Neurology·Leah H RubinDavid J Moore
Sep 4, 2020·AIDS and Behavior·Corrina MoucheraudRisa M Hoffman
Dec 22, 2020·Current Treatment Options in Infectious Diseases·Tessa Del CarmenEugenia L Siegler
Feb 23, 2021·Lancet·Adaora A AdimoraMonica Gandhi
Jan 14, 2021·Menopause : the Journal of the North American Menopause Society·Pauline M MakiLeah H Rubin
Jan 16, 2021·The Journal of the Association of Nurses in AIDS Care : JANAC·Drenna WaldropDavid E Vance
May 8, 2021·HIV/AIDS : Research and Palliative Care·Eugenia L SieglerMarshall J Glesby
Jun 6, 2021·Scientific Reports·Kristen A McLaurinRosemarie M Booze
Aug 22, 2021·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Anna J DreyerKevin G F Thomas
Nov 27, 2021·Neuropsychology Review·David E VancePariya L Fazeli
Nov 30, 2021·Current HIV/AIDS Reports·Michael J PelusoFelicia C Chow
Mar 20, 2020·Neurology. Clinical Practice·Sean G AndersonEric H Decloedt

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