Differences in effective connectivity between dyslexic children and normal readers during a pseudoword reading task: an fMRI study

Neurophysiologie clinique = Clinical neurophysiology
V QuaglinoG de Marco

Abstract

This fMRI study investigated phonological and lexicosemantic processing in dyslexic and in chronological age- and reading level-matched children in a pseudoword reading task. The effective connectivity network was compared between the three groups using a structural model including the supramarginal cortex (BA 40; BA: Brodmann area), fusiform cortex (BA 37) and inferior frontal cortex (BA 44/45) areas of the left hemisphere. The results revealed differences in connectivity patterns. In dyslexic patients, in contrast with chronological age- and reading level-matched groups, no causal relationship was demonstrated between BA 40 and BA 44/45. However, a significant causal relationship was demonstrated between BA 37 and BA 44/45 both in dyslexic children and in the reading level-matched group. These findings were interpreted as evidence for a phonological deficit in developmental dyslexia.

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Citations

Apr 11, 2013·Journal of Learning Disabilities·Sarit AshkenaziVinod Menon
Mar 27, 2009·Neuroscience Research·G de MarcoP Berquin
Apr 28, 2011·Human Brain Mapping·Suzanne E WelcomeElizabeth R Sowell
Jul 5, 2016·Frontiers in Neuroscience·Jessica W YoungerJames R Booth
Aug 1, 2016·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·G Fraga GonzálezM W Van der Molen
Jun 25, 2017·NeuroImage·Jessica Wise YoungerJames R Booth
Aug 31, 2020·Child Development·Fan CaoJames R Booth
Sep 15, 2018·Frontiers in Human Neuroscience·Gorka Fraga GonzálezMaurits W van der Molen
Dec 14, 2021·Frontiers in Psychology·Gorka Fraga-GonzálezMaurits W Van der Molen

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