Differences in heart rate dynamics before the spontaneous onset of long and short episodes of paroxysmal atrial fibrillation

Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
Saila VikmanHeikki V Huikuri

Abstract

Altered heart rate (HR) dynamics precede the spontaneous onset of atrial fibrillation (AF), but the factors related to the perpetuation and duration of paroxysmal AF episodes are not well established. This study was designed to test the hypothesis that HR dynamics preceding the onset of (AF) may influence the duration of AF. Traditional time and frequency domain HR variability indices, along with a short-term fractal scaling exponent (alpha(1)) and approximate entropy (ApEn), were analyzed in 20-minute intervals before 92 episodes of spontaneous paroxysmal AF in 22 patients without structural heart disease. AF episodes were divided into two groups according to the duration of the arrhythmia episodes. The high-frequency (HF) spectral component in normalized units (nu) of heart rate variability was higher and low-frequency (LF) component lower before long (> 200 s, n = 41) compared to short (< 200 s, n = 51) AF episodes (HF nu; 40.1 +/- 14.8 vs 31.5 +/- 16.4, P < 0.0001 and LF nu; 59.9 +/- 14.8 vs 68.5 +/- 16.4, P < 0.0001). Short-term scaling exponent values also were lower before long compared to short AF episodes (e.g., alpha(1); 1.12 +/- 0.21 vs 1.24 +/- 0.23, P < 0.0001). Women had a larger number of long AF episodes than me...Continue Reading

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Citations

Mar 10, 2009·Experimental Physiology·Anthony S LeichtSue Winter
Jan 15, 2004·Pacing and Clinical Electrophysiology : PACE·Mizuho MiyauchiTeruo Takano
Jan 18, 2005·Journal of the American College of Cardiology·Saila VikmanHeikki V Huikuri
Oct 22, 2016·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Wail NammasPasi P Karjalainen
May 3, 2008·Journal of Applied Physiology·Kevin S HeffernanBo Fernhall

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