Differences in morphology and contractility of the bulbospongiosus and pubococcygeus muscles in nulliparous and multiparous rabbits

International Urogynecology Journal and Pelvic Floor Dysfunction
Víctor FajardoMargarita Martínez-Gómez

Abstract

In women, birth trauma can result in altered anatomy of supporting structures of the pelvic floor and in the development of urinary incontinence. The goal of this study was to investigate the association between parturition and the morphology and function of perineal and pelvic muscles in the female rabbit. In ten nulliparous and ten multiparous same-age females, we investigated morphological, histological (n = 5 females/group), and contractile characteristics (n = 5 females/group) of the perineal bulbospongiosus (Bsm) and the pelvic pubococcygeus (Pcm) muscles. Bsm and Pcm muscles of multiparous females were significantly lighter, they had a smaller cross-sectional fiber area, and developed significantly lower twitch and tetanic tension force in response to electrical stimulation than muscles of nulliparous females. In female rabbits, multiparity is associated with potentially pathological changes in the morphological and functional characteristics of these perineal and pelvic muscles, possibly as a result of stretching during parturition.

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Citations

Nov 16, 2013·Acta histochemica·Kenia López-GarcíaFrancisco Castelán
May 15, 2013·European Journal of Obstetrics, Gynecology, and Reproductive Biology·K López-GarcíaF Castelán
May 21, 2010·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Karl B Thor, William C de Groat
May 26, 2017·Neurourology and Urodynamics·Rhode López-JuárezMargarita Martínez-Gómez
Jun 28, 2011·Reproductive Sciences·Margarita Martínez-GómezFrancisco Castelán
Sep 28, 2016·Neurourology and Urodynamics·Kenia López-GarcíaIsmael Jiménez-Estrada
Aug 12, 2014·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Nicte XelhuantziMargarita Martínez-Gómez
Dec 3, 2014·Neurourology and Urodynamics·Kenia López-GarcíaFrancisco Castelán
Jan 23, 2009·The Journal of Urology·Dora Luz Corona-QuintanillaMargarita Martínez-Gómez
Nov 26, 2009·The Journal of Comparative Neurology·Yolanda CruzRosa Angélica Lucio
Jan 24, 2021·International Urogynecology Journal·Marina Gabriela M C Mori da CunhaJan Deprest

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