PMID: 15247807Jul 13, 2004Paper

Differences in mortality by radiation monitoring status in an expanded cohort of Portsmouth Naval Shipyard workers

Journal of Occupational and Environmental Medicine
Sharon R SilverPi-Hsueh Chen

Abstract

Studies of leukemia and lung cancer mortality at the Portsmouth Naval Shipyard (PNS) have yielded conflicting results. In an expanded cohort of PNS workers employed between 1952 and 1992 and followed through 1996, the all-cause standardized mortality ratio (SMR) was 0.95 (95% confidence interval, 0.93-0.96). Employment duration SMRs were elevated with confidence intervals excluding 1.00 for lung cancer, esophageal cancer, and all cancers combined. Leukemia mortality was as expected overall, but standardized rate ratio analyses showed a significant positive linear trend with increasing external radiation dose. The role of solvent exposures could not be evaluated. Findings differed by radiation monitoring subcohort, with excess asbestosis deaths limited to radiation workers and several smoking-related causes of death higher among nonmonitored workers. At PNS, asbestos exposure and possibly smoking could be nonrandomly distributed with respect to radiation exposure, suggesting potential for confounding in internal analyses of an occupational cohort.

References

May 13, 1978·Lancet·T Najarian, T Colton
Jun 1, 1986·American Journal of Epidemiology·F B SternW E Murray
Jan 31, 1981·Lancet·R A RinskyC Cox
Sep 1, 1996·Occupational and Environmental Medicine·G M MarshK Y Lee
Jan 25, 2000·American Journal of Epidemiology·I Hertz-PicciottoS W Hu
Mar 21, 2000·American Journal of Industrial Medicine·K InnosD A Leon
Nov 14, 2001·Occupational and Environmental Medicine·U SiebertH Brenner

❮ Previous
Next ❯

Citations

Aug 19, 2007·Cancer Causes & Control : CCC·Sharon R SilverRobert D Daniels
Jan 1, 2014·Health Physics·Paul K Blake, Gregory R Komp
Jul 3, 2009·Occupational and Environmental Medicine·P JacobH Zeeb
Dec 17, 2009·Archives of Environmental & Occupational Health·C Metz-FlamantM Tirmarche
May 27, 2015·Radiation Research·Mary K Schubauer-BeriganDavid B Richardson
Jul 1, 2006·Radiation Research·John D BoiceBrian E Henderson
Jul 12, 2008·Journal of Occupational and Environmental Medicine·Yeon-Soon AhnDong-Hee Koh
Jul 11, 2019·International Journal of Radiation Biology·Michael T MummaWilliam J Blot
Jan 23, 2020·Critical Reviews in Toxicology·Michael K PetersonHeather Lynch

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Incidence & Mortality

Cancer has emerged as a global concern due to its increase in incidence and mortality. Efforts are underway to evaluate and develop action plans to reduce the global burden of cancer. Currently, lung cancer, breast cancer and prostate cancer are the leading causes of cancer mortality. Here is the latest research on cancer incidence and mortality.