PMID: 6110953Apr 4, 1981Paper

Differences in prognosis for boys and girls with acute lymphoblastic leukaemia

Lancet
H SatherD Hammond

Abstract

In the period 1968--78, 3161 children were enrolled in six studies of acute lymphoblastic leukaemia by participating institutions of the Childrens Cancer Study Group. In the first two studies, which did not include central-nervous-system (CNS) prophylaxis in the treatment programme, the outcome for male and female patients was very similar. In the following four studies, which included radiation prophylaxis to the CNS, a difference in outcome favouring females appeared consistently. This difference began about 6--12 months after initial remission and was further accentuated by withdrawal of therapy. Some of these studies also included a randomised trial of duration of therapy, studying 3 versus 5 years of maintenance treatment. Analysis of these studies suggests that sex group has implications both for duration of treatment and for optimum central-nervous-system prophylaxis.

References

Jul 15, 1978·Lancet·J H Baumer, M G Mott
Sep 2, 1978·Lancet·D I EvansM K Palmer
Feb 8, 1979·The New England Journal of Medicine·S L GeorgeJ V Simone
Jan 1, 1979·Medical and Pediatric Oncology·V J LandK Starling
Feb 1, 1968·Archives of Disease in Childhood·R M Hardisty, M M Till
Jul 1, 1996·Current Opinion in Hematology·C P Leith, C L Willman

❮ Previous
Next ❯

Citations

Jan 1, 1993·European Journal of Clinical Pharmacology·B KlemetsdalJ Aarbakke
Jul 1, 1981·Indian Journal of Pediatrics·H Ekert
Feb 1, 1990·Irish Journal of Medical Science·J ArmstrongS Cahalane
Jan 1, 1988·Irish Journal of Medical Science·B M CarrI J Temperley
Apr 3, 2007·Indian Journal of Pediatrics·A SettinY Al-Tonbary
Sep 1, 1995·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J M Chessells
Jul 7, 1983·The New England Journal of Medicine·R BraunerR Rappaport
Feb 1, 1995·British Journal of Haematology·J M ChessellsO B Eden
Apr 1, 1991·Archives of Disease in Childhood·J P Hale, J S Lilleyman
Oct 14, 2014·Journal of Cancer Epidemiology·Md Jobayer HossainSuzanne M McCahan
Aug 4, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Shilo RosenbergReuven Or
Apr 17, 2004·Journal of Pediatric Hematology/oncology·Eduard H PanosyanUNKNOWN Children's Cancer Group Study CCG-1961
Oct 1, 1983·British Journal of Haematology·R J StockleyM G Mott
Mar 30, 2006·Toxicological Sciences : an Official Journal of the Society of Toxicology·Ramadoss SivakumarKarundevi Balasubramanian
Jan 1, 1989·Pediatric Hematology and Oncology·L Russell, O B Eden
Jun 18, 2014·Journal of Pediatric Hematology/oncology·Kjeld SchmiegelowJacob Nersting
Jan 1, 1983·Medical and Pediatric Oncology·H P LinP Singh
Jan 1, 1986·Medical and Pediatric Oncology·H N Sather
Jan 1, 1983·Medical and Pediatric Oncology·C MagnaniB Terracini
Sep 1, 1984·Scandinavian Journal of Haematology·N ClausenJ Nyboe
Feb 28, 2017·Brain and Behavior·Ellen van der PlasBrian J Nieman
Jan 1, 1994·Medical and Pediatric Oncology·M J CoppesR Kay
Jan 1, 1997·Medical and Pediatric Oncology·Z AzizS Maqbool
Jan 1, 1986·Medical and Pediatric Oncology·A Russo, G Schiliro'
Jan 1, 1984·Medical and Pediatric Oncology·J J OrtegaN Torán

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.