Differences in regional systolic and diastolic function by Doppler tissue imaging in patients with hypertrophic cardiomyopathy and hypertrophy caused by hypertension

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
Juana NúñezCarlos Macaya

Abstract

Doppler tissue (DT) velocity abnormalities have been described in patients with pathologic left ventricular hypertrophy (LVH). Impaired myocardial function has been suggested as a primary disorder in hypertrophic cardiomyopathy (HCM) and differences in DT parameters have been reported to be distinguishable from other LVH causes. We evaluated DT differences for patients with LVH caused by hypertension and patients with HCM, assessing regional systolic and diastolic function. A total of 62 participants were studied: 21 with HCM; 22 with LVH secondary to hypertension; and 19 control subjects. DT was used to record mitral annulobasal segment motion in the longitudinal axis. Systolic and diastolic velocities were measured at lateral and septal sites, and well-known ratios were obtained for diastolic assessment. A new global function index (GFI) that evaluates both systole and diastole was also calculated (GFI = [Emi/E(DT)]/S(DT) [s x cm(-1)], where mi is mitral inflow, E is E wave, and S is systolic wave). Comparison showed significant differences in all parameters evaluated at the septal-basal segment and a GFI value of 1.77 showed 85% sensitivity and 75% specificity for detecting HCM when interventricular septum thickness was incr...Continue Reading

References

Jun 10, 1998·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·H YamadaS Ito

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Citations

Mar 17, 2010·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Suzanne EshooLiza Thomas
Mar 28, 2007·Heart Failure Clinics·Steven J FowlerSwaminatha V Gurudevan
Jul 15, 2009·Echocardiography·María C SaccheriLuis A Vidal
Nov 14, 2006·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Per LindqvistAnders Waldenström
Oct 2, 2007·Journal of Cardiovascular Medicine·Ayman A El-MenyarJassim Al Suwaidi
Mar 5, 2020·Revista Da Sociedade Brasileira De Medicina Tropical·Tomás Francisco CianciulliJorge Alberto Lax

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