Differences in Retinal Nerve Fiber Layer Thickness as Assessed on the Disc Center and Bruch's Membrane Opening Center in Myopic Eyes.

Ophthalmology. Glaucoma
Yu SawadaTakeshi Yoshitomi

Abstract

To investigate the difference in circumpapillary retinal nerve fiber layer thickness (cpRNFLT) assessed on the conventional, clinically identified optic disc center and Bruch's membrane opening (BMO) center in myopic eyes. Cross-sectional study. One hundred nine eyes of 109 healthy myopic subjects with axial length of 24 mm or more. The cpRNFLT was acquired on the disc center and BMO center aligned with the fovea. The global and sectorial cpRNFLT were computed in each eye and were compared between the 2 assessments. Furthermore, factors associated with the difference in cpRNFLT between the 2 assessments were analyzed. Differences in cpRNFLT assessed on the disc center and BMO center in myopic eyes. Among the included participants, the mean SE was -4.94±1.69 D, and the mean axial length was 25.55±0.89 mm. The global cpRNFLT was not significantly different between the 2 assessments; however, the temporal sector was significantly thicker, and the nasal sector was significantly thinner in the assessment on the disc center than on the BMO center (P < 0.0001 for both). Forty eyes (36.7%) exhibited more than 10 μm of difference between the 2 assessments in the temporal sector. The positions of the superior and inferior peaks of the cp...Continue Reading

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