Differences in Speed of Response of Depressive Symptom Dimensions in Older Persons During Electroconvulsive Therapy

The Journal of ECT
Eveline VeltmanDidi Rhebergen

Abstract

Electroconvulsive therapy (ECT) is an important and effective treatment for depression. However, research on course trajectories of depressive symptoms during ECT is limited. Insight into putative differences in speed of response of depressive symptom dimensions may enable clinicians to optimally inform patients and their relatives. Therefore, we aim to examine course trajectories of depressive symptom dimensions in depressed older persons during ECT. Data were derived from the Mood Disorders in Elderly treated with Electro Convulsive Therapy study, including 110 persons, aged 55 years or more, with a current diagnosis of major depressive disorder and referred for ECT. Exploratory factor analysis was used to identify symptom dimensions, using the 10 depression items of the Montgomery-Åsberg Depression Rating Scale (MADRS). Differences in course trajectories of symptom dimension during 2 weeks were examined by multilevel analyses. Three symptom dimensions were identified: a "mood," "melancholic," and "suicidal" dimension. Mood showed a significantly greater severity decline as compared with melancholic and suicidal at the 1-week follow-up. At the 2-week follow-up, both mood and melancholic demonstrated a significantly greater de...Continue Reading

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Citations

Feb 19, 2019·Australasian Psychiatry : Bulletin of Royal Australian and New Zealand College of Psychiatrists·Tamara May, Saxby Pridmore
Feb 16, 2021·Acta Psychiatrica Scandinavica·Celine A Fox, Declan M McLoughlin
Feb 24, 2021·Progress in Neuro-psychopharmacology & Biological Psychiatry·Akihiro TakamiyaMasaru Mimura

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