Differences in Symptom Severity and Quality of Life in Patients With Obstructive Defecation and Colonic Inertia

Diseases of the Colon and Rectum
Adriana B ChouM G Varma

Abstract

Little is known about how obstructive defecation and colonic inertia symptoms contribute to constipation-related quality of life. We sought to characterize the differences in quality of life in patients with severe obstructive defecation and colonic inertia symptoms. This study was a cross-sectional analysis of a prospective database. Patients were enrolled at a single tertiary referral center. We included consecutive adults with severe symptoms of obstructive defecation (n = 115) or colonic inertia (n = 90) as measured by the Constipation Severity Instrument. The primary outcomes measured were the Pelvic Floor Distress Inventory, Constipation-Related Quality of Life instrument, Pelvic Floor Impact Questionnaire, and 12-item Short Form Health Survey. Although physical examination and anorectal physiology testing were similar between groups, patients with severe obstructive defecation symptoms reported worse pain, distress, and constipation-specific quality of life than patients with severe colonic inertia symptoms (all p < 0.001). Specifically, patients with severe obstructive defecation symptoms showed greater quality-of-life impairment related to eating, bathroom habits, and social functioning (all p ≤ 0.01). Furthermore, pat...Continue Reading

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Citations

Jun 9, 2016·Expert Opinion on Investigational Drugs·Gabrio BassottiMassimo Bellini
Nov 25, 2020·Journal of the Chinese Medical Association : JCMA·Yi-Jian TsaiYuan-Tzu Lan

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