Differences in the equine faecal microbiota between horses presenting to a tertiary referral hospital for colic compared with an elective surgical procedure

Equine Veterinary Journal
H L StewartDipti W Pitta

Abstract

The faecal microbiota is emerging as potentially important in intestinal disease. More research is needed to characterise the faecal microbiota from horses with colic. To compare the relative abundance of bacterial populations comprising the faecal microbiota in horses presenting for colic compared with an elective surgical procedure. Prospective observational clinical study. Admission faecal samples were collected from horses presenting for colic and elective surgical procedures. Faecal samples were extracted for genomic DNA, PCR- amplified, sequenced and analysed using QIIME. Species richness and Shannon diversity were estimated for each faecal sample. The extent of the relationship between bacterial communities (beta diversity) was quantified using pairwise UniFrac distances, visualised using principal coordinate analysis (PCoA) and statistically analysed using PERMANOVA. The relative abundance of bacterial populations between the two treatment groups were compared using ANCOM. Faecal bacterial communities in horses presenting for colic had fewer species (P<0.001) and lower diversity (P<0.001) compared with horses presenting for elective surgical procedures. Based on the PERMANOVA analysis, there was a significant difference...Continue Reading

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Citations

Oct 5, 2019·Equine Veterinary Journal·P R Murcia
Sep 14, 2020·Equine Veterinary Journal·Nicola WalsheVivienne Duggan
Mar 7, 2021·Animals : an Open Access Journal From MDPI·Christina Wimmer-ScherrCarla Cesarini
Jun 3, 2021·Animals : an Open Access Journal From MDPI·Yiping ZhuJing Li
Jul 10, 2021·Frontiers in Genetics·Seika Hashimoto-Hill, Theresa Alenghat
Jul 3, 2021·Animals : an Open Access Journal From MDPI·Mathijs J P TheelenAldert L Zomer
Aug 8, 2021·Animals : an Open Access Journal From MDPI·Alexa C B Johnson, Amy S Biddle
Aug 22, 2021·Journal of Equine Veterinary Science·Ana BerretaClaire R Burbick
Jan 22, 2022·Veterinary Medicine and Science·Monica AlemanJonathan Eisen

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